SCHEMBL1172853

SCHEMBL1172853

CC1C(=O)C2(C)CCC1C2

nearest known ligand 0.33

Predicted protein targets (top 1)

geneUniProtsupporting neighboursconfidence
STAT1 P42224 1/20 0.31

Click a target to see other patent compounds predicted against it — the reverse direction, in place.

Similar compounds — the chemically nearest patent molecules

Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.

Compoundsimilaritytop predictedshared targets
SCHEMBL12506427 0.88 STAT1 (0.32) STAT1
SCHEMBL1119662 0.77
SCHEMBL5872640 0.75
SCHEMBL27583833 0.69
SCHEMBL30378162 0.68
SCHEMBL1277001 0.68 TSHR (0.36)
SCHEMBL11224933 0.68 CYP3A4 (0.33)
SCHEMBL24483649 0.64 ICAM1 (0.35)
SCHEMBL24483980 0.64 ICAM1 (0.35)
SCHEMBL21596725 0.60 MAPT (0.33)

Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.

Patent provenance — the patents this molecule appears in, and who filed them

Claimed or disclosed in 28 patents — showing the first 20. claimed = in the patent's claims; disclosed = body only.

PatentTitleAssigneePublishedPriorityFilingCountryStatus
WO-2007076318-A2 CAMPHOR-DERIVED CXCR3 ANTAGONISTS SMITHKLINE BEECHAM CORPORATION (US) 2007-07-05 WO claimed
CN-105473554-B Condensed piperidine amide as ion channel modulators 沃泰克斯药物股份有限公司 2019-08-13 CN disclosed
US-20170066727-A1 Photostabilizing Compounds and Methods of Making and Using the Same ELEVANCE RENEWABLE SCIENCES, INC. (US) 2017-03-09 US disclosed
US-20170066727-A1 Photostabilizing Compounds and Methods of Making and Using the Same ELEVANCE RENEWABLE SCIENCES, INC. (US) 2017-03-09 US disclosed
US-8986662-B2 Use of silane and siloxane bis(biphenyl) triazine derivatives as UV absorbers BASF SE (DE) 2015-03-24 US disclosed
US-8529877-B2 Benzylidene compounds comprising phosphono-groups BASF SE (DE) 2013-09-10 US disclosed
US-20130202542-A1 USE OF SILANE AND SILOXANE BIS(BIPHENYL) TRIAZINE DERIVATIVES AS UV ABSORBERS BASF SE (DE) 2013-08-08 US disclosed
US-8404705-B2 Naphthalene amidine imides BASF SE (DE) 2013-03-26 US disclosed
US-20110212039-A1 BENZYLIDENE COMPOUNDS COMPRISING PHOSPHONO-GROUPS BASF SE (DE) 2011-09-01 US disclosed
US-20110038815-A1 DIMERIC BENZYLIDENE MALONATES BASF SE (DE) 2011-02-17 US disclosed
US-7105570-B2 Cysteine derivatives AJINOMOTO CO., INC. (JP) 2006-09-12 US disclosed
US-7038046-B2 Triazine derivatives and their use as sunscreens CIBA SPECIALTY CHEMICALS CORPORATION (US) 2006-05-02 US disclosed
US-6984735-B2 Reacting a dihalaromatic compound with sulfoxide WYETH (US) 2006-01-10 US disclosed
US-20050058610-A1 Cosmetic mixtures containing ultraviolet radiation absorber and decoloring agents CIBA SPECIALTY CHEMICALS CORP. 2005-03-17 US disclosed
US-20040082785-A1 Process for making an aldehyde WYETH 2004-04-29 US disclosed
US-6703031-B1 OXIDATIVE STRESS INHIBITOR; RETARDING AGING OF SKIN AJINOMOTO CO., INC. (JP) 2004-03-09 US disclosed
US-6680390-B2 SUNSCREEN AGENTS BASF AKTIENGESELLSCHAFT (DE) 2004-01-20 US disclosed
US-6569355-B1 Pigments; pyrano(3,2-d)dioxane esters substituted with polymerizable acrylate groups; cosmetics BASF AKTIENGESELLSCHAFT (DE) 2003-05-27 US disclosed
US-6524560-B1 Light protection agents for cosmetics and pharmaceuticals which absorb predominantly in ultraviolet-A region with high absorbance, are photostable, have low intrinsic color, and are soluble in oil or water depending on substituent BASF AKTIENGESELLSCHAFT (DE) 2003-02-25 US disclosed
EP-1120407-A1 CYSTEINE DERIVATIVES Ajinomoto Co., Inc. (JP) 2001-08-01 EP disclosed

Patent text — is the patent's own abstract consistent with the prediction?

For each of this compound's patents that has machine-readable text (6 of them — usually the abstract, not the full specification), we ask MedCPT which protein the text reads most about, and where the chemistry-predicted target lands among 4885 human targets. A high rank means the patent's own wording is consistent with the prediction — a weak, independent signal, not proof of activity.

PatentTitleText reads most aboutPredicted target · text-rank
US-20110212039-A1 BENZYLIDENE COMPOUNDS COMPRISING PHOSPHONO-GROUPS NR1H2, ESRRA, NR1H3 STAT1 2380/4885
US-20050058610-A1 Cosmetic mixtures containing ultraviolet radiation absorber and decoloring agents TYR, MC1R, UNG STAT1 3383/4885
US-20170066727-A1 Photostabilizing Compounds and Methods of Making and Using the Same SQLE, NQO1, TYR STAT1 2737/4885
US-20110038815-A1 DIMERIC BENZYLIDENE MALONATES C1R, COPS6, CBR3 STAT1 2594/4885
US-20130202542-A1 USE OF SILANE AND SILOXANE BIS(BIPHENYL) TRIAZINE DERIVATIVES AS UV ABSORBERS CCNL2, MSR1, CYP2S1 STAT1 2442/4885
US-20040082785-A1 Process for making an aldehyde ALDH7A1, ALDH2, ALDH18A1 STAT1 2550/4885

“Text reads most about” is the patent abstract's nearest protein in MedCPT space (background-debiased). Only ~1.4% of patents have machine-readable text, so most compounds won't have this panel.