Predicted protein targets (top 16)
| gene | UniProt | supporting neighbours | confidence | |
|---|---|---|---|---|
| ▸ | DRD3 | P35462 | 7/20 | 0.43 |
| ▸ | DRD4 | P21917 | 6/20 | 0.43 |
| ▸ | DRD2 | P14416 | 5/20 | 0.43 |
| ▸ | GAA | P10253 | 2/20 | 0.36 |
| ▸ | ADRB1 | P08588 | 1/20 | 0.35 |
| ▸ | HTR6 | P50406 | 1/20 | 0.35 |
| ▸ | MAPK14 | Q16539 | 1/20 | 0.34 |
| ▸ | CNR2 | P34972 | 2/20 | 0.34 |
| ▸ | L3MBTL1 | Q9Y468 | 1/20 | 0.34 |
| ▸ | OPRM1 | P35372 | 1/20 | 0.33 |
| ▸ | OPRK1 | P41145 | 1/20 | 0.33 |
| ▸ | KDM4E | B2RXH2 | 1/20 | 0.33 |
| ▸ | MAPT | P10636 | 1/20 | 0.33 |
| ▸ | HCRTR1 | O43613 | 1/20 | 0.32 |
| ▸ | HCRTR2 | O43614 | 1/20 | 0.32 |
| ▸ | HPGDS | O60760 | 1/20 | 0.32 |
Click a target to see other patent compounds predicted against it — the reverse direction, in place.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| SCHEMBL11140740 | 0.91 | DRD3 (0.43) | DRD3DRD4DRD2GAA | |
| SCHEMBL11134587 | 0.85 | DRD2 (0.43) | DRD3DRD4DRD2CNR2OPRM1 | |
| SCHEMBL11136336 | 0.85 | DRD4 (0.51) | DRD3DRD4DRD2GAAMAPK14 | |
| SCHEMBL11131756 | 0.85 | DRD3 (0.41) | DRD3DRD4DRD2GAAADRB1 | |
| SCHEMBL10675284 | 0.85 | DRD4 (0.46) | DRD3DRD4DRD2GAAADRB1 | |
| Hydrochloric Acid SCHEMBL11220155 | 0.84 | DRD4 (0.50) | DRD3DRD4DRD2GAAMAPK14 | |
| SCHEMBL11131906 | 0.84 | ADRB1 (0.37) | DRD3DRD4DRD2GAAADRB1 | |
| SCHEMBL11223325 | 0.83 | SLC6A3 (0.42) | DRD3DRD4DRD2MAPK14L3MBTL1 | |
| SCHEMBL10674194 | 0.78 | DRD3 (0.45) | DRD3DRD4DRD2OPRM1 | |
| SCHEMBL7951002 | 0.75 | DRD2 (0.41) | DRD3DRD4DRD2GAAADRB1 |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 1 patent. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| US-4332808-A | Dopaminergically stimulating 4-substituted indoles | ROUSSEL UCLAF (FR) | 1982-06-01 | — | — | US | disclosed |