Predicted protein targets (top 20)
| gene | UniProt | supporting neighbours | confidence | |
|---|---|---|---|---|
| ▸ | MAPT | P10636 | 3/20 | 0.60 |
| ▸ | KMT2A | Q03164 | 2/20 | 0.60 |
| ▸ | MEN1 | O00255 | 1/20 | 0.60 |
| ▸ | SMN1; SMN2 | Q16637 | 1/20 | 0.60 |
| ▸ | TSHR | P16473 | 3/20 | 0.53 |
| ▸ | GFER | P55789 | 1/20 | 0.53 |
| ▸ | MAPK1 | P28482 | 2/20 | 0.53 |
| ▸ | CA1 | P00915 | 1/20 | 0.53 |
| ▸ | CA2 | P00918 | 1/20 | 0.53 |
| ▸ | CA9 | Q16790 | 1/20 | 0.53 |
| ▸ | L3MBTL1 | Q9Y468 | 1/20 | 0.52 |
| ▸ | GAA | P10253 | 3/20 | 0.49 |
| ▸ | ALDH1A1 | P00352 | 3/20 | 0.49 |
| ▸ | KDM4E | B2RXH2 | 3/20 | 0.49 |
| ▸ | APOBEC3G | Q9HC16 | 2/20 | 0.49 |
| ▸ | ALOX15 | P16050 | 1/20 | 0.47 |
| ▸ | NPSR1 | Q6W5P4 | 1/20 | 0.47 |
| ▸ | TDP1 | Q9NUW8 | 1/20 | 0.47 |
| ▸ | FABP1 | P07148 | 2/20 | 0.44 |
| ▸ | HTT | P42858 | 1/20 | 0.44 |
Click a target to see other patent compounds predicted against it — the reverse direction, in place.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| SCHEMBL29352125 | 0.72 | KMT2A (0.51) | MAPTKMT2AMEN1SMN1; SMN2TSHR | |
| SCHEMBL4340669 | 0.72 | KMT2A (0.51) | MAPTKMT2AMEN1SMN1; SMN2TSHR | |
| SCHEMBL26107557 | 0.72 | L3MBTL1 (0.68) | MAPTKMT2AMEN1SMN1; SMN2TSHR | |
| SCHEMBL5422444 | 0.72 | L3MBTL1 (0.76) | MAPTKMT2AMEN1SMN1; SMN2TSHR | |
| SCHEMBL27592567 | 0.71 | MAPK1 (0.70) | MAPTKMT2AMEN1SMN1; SMN2TSHR | |
| SCHEMBL7180056 | 0.71 | MAPK1 (0.70) | MAPTKMT2AMEN1SMN1; SMN2TSHR | |
| SCHEMBL31684035 | 0.71 | L3MBTL1 (0.74) | MAPTKMT2AMEN1SMN1; SMN2TSHR | |
| SCHEMBL11679037 | 0.70 | MAPK1 (0.68) | MAPTKMT2AMEN1SMN1; SMN2TSHR | |
| SCHEMBL51046 | 0.70 | MAPK1 (0.68) | MAPTKMT2AMEN1SMN1; SMN2TSHR | |
| SCHEMBL50688 | 0.70 | MAPK1 (1.00) | MAPTKMT2AMEN1SMN1; SMN2TSHR |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 2 patents. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| JP-57116067-A | — | — | None | — | — | JP | disclosed |
| JP-S57116067-A | NOVEL 8-QUINOLINESULFONYL DERIVATIVE, ITS SYNTHESIS AND USE | SANKYO KAGAKU KK | 1982-07-19 | — | — | JP | disclosed |