Predicted protein targets (top 17)
| gene | UniProt | supporting neighbours | confidence | |
|---|---|---|---|---|
| ▸ | ADRB2 | P07550 | 3/20 | 0.57 |
| ▸ | ADRB1 | P08588 | 3/20 | 0.57 |
| ▸ | CYP2D6 | P10635 | 2/20 | 0.57 |
| ▸ | ADRB3 | P13945 | 1/20 | 0.57 |
| ▸ | NR2E1 | Q9Y466 | 1/20 | 0.46 |
| ▸ | PTGS1 | P23219 | 2/20 | 0.44 |
| ▸ | MAOA | P21397 | 1/20 | 0.44 |
| ▸ | LMNA | P02545 | 1/20 | 0.44 |
| ▸ | NR3C1 | P04150 | 1/20 | 0.43 |
| ▸ | ADRA1A | P35348 | 1/20 | 0.43 |
| ▸ | CYP2J2 | P51589 | 1/20 | 0.43 |
| ▸ | PDE4D | Q08499 | 1/20 | 0.43 |
| ▸ | SLC6A2 | P23975 | 1/20 | 0.42 |
| ▸ | MAPT | P10636 | 1/20 | 0.40 |
| ▸ | MEN1 | O00255 | 1/20 | 0.40 |
| ▸ | ALDH1A1 | P00352 | 1/20 | 0.40 |
| ▸ | KMT2A | Q03164 | 1/20 | 0.40 |
Click a target to see other patent compounds predicted against it — the reverse direction, in place.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| SCHEMBL7270606 | 0.84 | LMNA (0.50) | ADRB2ADRB1CYP2D6ADRB3PTGS1 | |
| SCHEMBL11222594 | 0.82 | ADRB2 (0.57) | ADRB2ADRB1CYP2D6ADRB3NR2E1 | |
| SCHEMBL10595267 | 0.78 | ADRB1 (0.68) | ADRB2ADRB1CYP2D6LMNANR3C1 | |
| SCHEMBL7917172 | 0.77 | ADRB2 (0.57) | ADRB2ADRB1CYP2D6ADRB3NR2E1 | |
| SCHEMBL8266174 | 0.73 | ADRB2 (1.00) | ADRB2ADRB1CYP2D6ADRB3PTGS1 | |
| SCHEMBL7367812 | 0.73 | ADRB2 (1.00) | ADRB2ADRB1CYP2D6ADRB3PTGS1 | |
| Hydrochloric Acid SCHEMBL10872169 | 0.72 | ADRB2 (0.97) | ADRB2ADRB1CYP2D6ADRB3PTGS1 | |
| SCHEMBL11232155 | 0.72 | ADRB2 (0.88) | ADRB2ADRB1CYP2D6ADRB3PTGS1 | |
| SCHEMBL17171595 | 0.69 | LMNA (0.57) | ADRB2ADRB1CYP2D6ADRB3PTGS1 | |
| SCHEMBL11667770 | 0.69 | ADRB2 (0.88) | ADRB2ADRB1CYP2D6ADRB3PTGS1 |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 2 patents. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| US-4360464-A | Process for production of 1-aryloxy-aminopropane derivatives | TEIKOKU HORMONE MFG. CO. LTD. (JP) | 1982-11-23 | — | — | US | disclosed |
| US-4018824-A | ANTIULCER AND ADRENERGIC BLOCKING AGENTS | TEIKOKU HORMONE MFG. CO., LTD. (JA) | 1977-04-19 | — | — | US | disclosed |