Predicted protein targets (top 20)
| gene | UniProt | supporting neighbours | confidence | |
|---|---|---|---|---|
| ▸ | KMT2A | Q03164 | 2/20 | 0.69 |
| ▸ | GAA | P10253 | 1/20 | 0.65 |
| ▸ | MMP2 | P08253 | 2/20 | 0.63 |
| ▸ | MMP7 | P09237 | 2/20 | 0.63 |
| ▸ | MMP14 | P50281 | 2/20 | 0.63 |
| ▸ | HSD11B1 | P28845 | 2/20 | 0.58 |
| ▸ | MMP1 | P03956 | 1/20 | 0.56 |
| ▸ | MMP3 | P08254 | 1/20 | 0.56 |
| ▸ | MMP9 | P14780 | 1/20 | 0.56 |
| ▸ | MMP13 | P45452 | 1/20 | 0.56 |
| ▸ | TP53 | P04637 | 1/20 | 0.54 |
| ▸ | MAPT | P10636 | 1/20 | 0.54 |
| ▸ | HPGD | P15428 | 1/20 | 0.54 |
| ▸ | MAPK1 | P28482 | 1/20 | 0.54 |
| ▸ | RAB9A | P51151 | 1/20 | 0.54 |
| ▸ | BCL2A1 | Q16548 | 1/20 | 0.54 |
| ▸ | NPSR1 | Q6W5P4 | 1/20 | 0.54 |
| ▸ | HSD17B10 | Q99714 | 1/20 | 0.54 |
| ▸ | TLR9 | Q9NR96 | 1/20 | 0.54 |
| ▸ | PHGDH | O43175 | 2/20 | 0.52 |
Click a target to see other patent compounds predicted against it — the reverse direction, in place.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| SCHEMBL2024141 | 0.90 | KMT2A (0.73) | KMT2AGAAHSD11B1TP53MAPT | |
| SCHEMBL13299621 | 0.89 | KMT2A (0.71) | KMT2AGAAMMP2MMP7MMP14 | |
| SCHEMBL6751981 | 0.89 | KMT2A (0.71) | KMT2AGAAHSD11B1TP53MAPT | |
| SCHEMBL27466607 | 0.85 | LMNA (0.63) | KMT2AGAAMMP2MMP7MMP14 | |
| SCHEMBL13299638 | 0.84 | KMT2A (0.64) | KMT2AGAAMMP2MMP7MMP14 | |
| SCHEMBL2178479 | 0.83 | KMT2A (0.78) | KMT2AGAAHSD11B1MAPTNPSR1 | |
| SCHEMBL13299631 | 0.83 | MMP2 (0.57) | KMT2AGAAMMP2MMP7MMP14 | |
| SCHEMBL18503840 | 0.82 | KMT2A (1.00) | KMT2AGAAHSD11B1TP53MAPT | |
| SCHEMBL23703133 | 0.81 | KMT2A (0.73) | KMT2AGAAHSD11B1TP53MAPT | |
| SCHEMBL1939652 | 0.81 | KMT2A (0.73) | KMT2AGAAHSD11B1MAPTHPGD |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 7 patents. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| EP-2529793-B1 | Compositions for regulating or modulating quorum sensing in bacteria, methods of using the compounds, and methods of regulating or modulating quorum sensing in bacteria | UNIV GEORGIA STATE RES FOUND (US) | 2016-08-10 | — | — | EP | disclosed |
| US-8653258-B2 | Compositions for regulating or modulating quorum sensing in bacteria, methods of using the compounds, and methods of regulating or modulating quorum sensing in bacteria | GEORGIA STATE UNIVERSITY RESEARCH FOUNDATION, INC. (US) | 2014-02-18 | — | — | US | disclosed |
| EP-2529793-A2 | Compositions for regulating or modulating quorum sensing in bacteria, methods of using the compounds, and methods of regulating or modulating quorum sensing in bacteria | Georgia State University Research Foundation, Inc. (US) | 2012-12-05 | — | — | EP | disclosed |
| US-20100137249-A1 | COMPOSITIONS FOR REGULATING OR MODULATING QUORUM SENSING IN BACTERIA, METHODS OF USING THE COMPOUNDS, AND METHODS OF REGULATING OR MODULATING QUORUM SENSING IN BACTERIA | GEORGIA STATE UNIVERSITY RESEARCH FOUNDATION, INC. | 2010-06-03 | — | — | US | disclosed |
| US-20100137249-A1 | COMPOSITIONS FOR REGULATING OR MODULATING QUORUM SENSING IN BACTERIA, METHODS OF USING THE COMPOUNDS, AND METHODS OF REGULATING OR MODULATING QUORUM SENSING IN BACTERIA | GEORGIA STATE UNIVERSITY RESEARCH FOUNDATION, INC. | 2010-06-03 | — | — | US | disclosed |
| WO-2009029317-A2 | COMPOSITIONS FOR REGULATING OR MODULATING QUORUM SENSING IN BACTERIA, METHODS OF USING THE COMPOUNDS, AND METHODS OF REGULATING OR MODULATING QUORUM SENSING IN BACTERIA | GEORGIA STATE UNIVERSITY RESEARCH FOUNDATION, INC. (US) | 2009-03-05 | — | — | WO | disclosed |
| US-4326066-A | Triazolyl coumarin compounds, processes for their preparation and their use as whiteners and laser dyestuffs | BAYER AKTIENGESELLSCHAFT (DE) | 1982-04-20 | — | — | US | disclosed |
Patent text — is the patent's own abstract consistent with the prediction?
For each of this compound's patents that has machine-readable text (1 of them — usually the abstract, not the full specification), we ask MedCPT which protein the text reads most about, and where the chemistry-predicted target lands among 4885 human targets. A high rank means the patent's own wording is consistent with the prediction — a weak, independent signal, not proof of activity.
| Patent | Title | Text reads most about | Predicted target · text-rank |
|---|---|---|---|
| US-20100137249-A1 | COMPOSITIONS FOR REGULATING OR MODULATING QUORUM SENSING IN BACTERIA, METHODS OF USING THE COMPOUNDS, AND METHODS OF REGULATING OR MODULATING QUORUM SENSING IN BACTERIA | ANTXR2, BLVRB, HACL2 | KMT2A 1355/4885GAA 3334/4885MMP2 2667/4885 |
“Text reads most about” is the patent abstract's nearest protein in MedCPT space (background-debiased). Only ~1.4% of patents have machine-readable text, so most compounds won't have this panel.