Predicted protein targets (top 11)
| gene | UniProt | supporting neighbours | confidence | |
|---|---|---|---|---|
| ▸ | RAB9A | P51151 | 10/20 | 0.62 |
| ▸ | NPC1 | O15118 | 9/20 | 0.62 |
| ▸ | MEN1 | O00255 | 2/20 | 0.56 |
| ▸ | KMT2A | Q03164 | 2/20 | 0.56 |
| ▸ | PKM | P14618 | 1/20 | 0.48 |
| ▸ | KDM4E | B2RXH2 | 1/20 | 0.45 |
| ▸ | GAA | P10253 | 1/20 | 0.45 |
| ▸ | SMN1; SMN2 | Q16637 | 1/20 | 0.44 |
| ▸ | TP53 | P04637 | 2/20 | 0.44 |
| ▸ | EPHX1 | P07099 | 1/20 | 0.43 |
| ▸ | MDM4 | O15151 | 1/20 | 0.42 |
Click a target to see other patent compounds predicted against it — the reverse direction, in place.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| SCHEMBL1620748 | 0.84 | KDM4E (0.65) | RAB9ANPC1MEN1KMT2AKDM4E | |
| SCHEMBL4786596 | 0.83 | KDM4E (0.56) | RAB9ANPC1MEN1KMT2AKDM4E | |
| SCHEMBL483417 | 0.78 | GAA (0.46) | RAB9ANPC1MEN1KMT2AKDM4E | |
| SCHEMBL10878176 | 0.76 | RAB9A (1.00) | RAB9ANPC1MEN1KMT2APKM | |
| SCHEMBL13132689 | 0.75 | NPC1 (0.57) | RAB9ANPC1MEN1KMT2APKM | |
| SCHEMBL13132543 | 0.75 | NPC1 (0.57) | RAB9ANPC1MEN1KMT2APKM | |
| SCHEMBL30499831 | 0.75 | NTRK1 (0.52) | RAB9ANPC1MEN1KMT2AKDM4E | |
| SCHEMBL11011942 | 0.74 | GAA (0.48) | KDM4EGAASMN1; SMN2 | |
| SCHEMBL5287605 | 0.74 | CFD (0.61) | MEN1KMT2AKDM4EGAASMN1; SMN2 | |
| SCHEMBL29022200 | 0.74 | NPC1 (0.45) | RAB9ANPC1MEN1KMT2AGAA |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 2 patents. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| US-4321276-A | INSECTICIDE | CIBA-GEIGY CORPORATION (US) | 1982-03-23 | — | — | US | disclosed |
| US-4321276-A | INSECTICIDE | CIBA-GEIGY CORPORATION (US) | 1982-03-23 | — | — | US | disclosed |