Predicted protein targets (top 20)
| gene | UniProt | supporting neighbours | confidence | |
|---|---|---|---|---|
| ▸ | GAA | P10253 | 5/20 | 0.46 |
| ▸ | KDM4E | B2RXH2 | 5/20 | 0.46 |
| ▸ | ALDH1A1 | P00352 | 5/20 | 0.41 |
| ▸ | LMNA | P02545 | 1/20 | 0.41 |
| ▸ | L3MBTL1 | Q9Y468 | 2/20 | 0.41 |
| ▸ | PLA2G7 | Q13093 | 1/20 | 0.40 |
| ▸ | NPC1 | O15118 | 1/20 | 0.39 |
| ▸ | RAB9A | P51151 | 1/20 | 0.39 |
| ▸ | HPGD | P15428 | 3/20 | 0.39 |
| ▸ | POLB | P06746 | 1/20 | 0.39 |
| ▸ | MEN1 | O00255 | 1/20 | 0.39 |
| ▸ | KMT2A | Q03164 | 1/20 | 0.39 |
| ▸ | TDP1 | Q9NUW8 | 1/20 | 0.39 |
| ▸ | TSHR | P16473 | 1/20 | 0.38 |
| ▸ | CXCR2 | P25025 | 1/20 | 0.38 |
| ▸ | GLA | P06280 | 1/20 | 0.38 |
| ▸ | NLRP3 | Q96P20 | 1/20 | 0.38 |
| ▸ | CYP1A2 | P05177 | 1/20 | 0.37 |
| ▸ | SMN1; SMN2 | Q16637 | 1/20 | 0.37 |
| ▸ | PDK1 | Q15118 | 1/20 | 0.37 |
Click a target to see other patent compounds predicted against it — the reverse direction, in place.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| SCHEMBL28259226 | 0.94 | GAA (0.42) | GAAKDM4EALDH1A1LMNAL3MBTL1 | |
| SCHEMBL4786596 | 0.86 | KDM4E (0.56) | GAAKDM4EALDH1A1LMNAL3MBTL1 | |
| SCHEMBL11011942 | 0.84 | GAA (0.48) | GAAKDM4EALDH1A1LMNAL3MBTL1 | |
| SCHEMBL3048096 | 0.82 | ALDH1A1 (0.55) | ALDH1A1L3MBTL1NPC1RAB9AHPGD | |
| SCHEMBL3473060 | 0.82 | MEN1 (0.45) | GAAKDM4ELMNANPC1RAB9A | |
| SCHEMBL4766358 | 0.80 | GAA (0.69) | GAAKDM4EALDH1A1LMNAL3MBTL1 | |
| SCHEMBL1542594 | 0.78 | PDK1 (0.50) | NPC1RAB9AMEN1KMT2APDK1 | |
| SCHEMBL29824473 | 0.78 | PDK1 (0.50) | NPC1RAB9AMEN1KMT2APDK1 | |
| SCHEMBL4862187 | 0.78 | L3MBTL1 (0.54) | GAAKDM4EALDH1A1L3MBTL1PLA2G7 | |
| SCHEMBL28019538 | 0.78 | GAA (0.53) | GAAKDM4EALDH1A1LMNANPC1 |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 2 patents. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| EP-2411057-A2 | IMAGING AGENTS FOR DETECTING NEUROLOGICAL DISORDERS | Siemens Medical Solutions USA, Inc. (US) | 2012-02-01 | — | — | EP | disclosed |
| WO-2010111303-A2 | IMAGING AGENTS FOR DETECTING NEUROLOGICAL DISORDERS | SIEMENS MEDICAL SOLUTIONS USA, INC. (US) | 2010-09-30 | — | — | WO | disclosed |