Predicted protein targets (top 20)
| gene | UniProt | supporting neighbours | confidence | |
|---|---|---|---|---|
| ▸ | KDM4E | B2RXH2 | 7/20 | 0.56 |
| ▸ | GAA | P10253 | 5/20 | 0.56 |
| ▸ | ALDH1A1 | P00352 | 4/20 | 0.50 |
| ▸ | NPC1 | O15118 | 4/20 | 0.50 |
| ▸ | RAB9A | P51151 | 4/20 | 0.50 |
| ▸ | SMN1; SMN2 | Q16637 | 3/20 | 0.50 |
| ▸ | GLA | P06280 | 1/20 | 0.50 |
| ▸ | CYP1A2 | P05177 | 1/20 | 0.49 |
| ▸ | RECQL | P46063 | 1/20 | 0.47 |
| ▸ | ALOX15 | P16050 | 1/20 | 0.46 |
| ▸ | HSD17B10 | Q99714 | 1/20 | 0.46 |
| ▸ | CXCR2 | P25025 | 1/20 | 0.46 |
| ▸ | CA12 | O43570 | 2/20 | 0.45 |
| ▸ | CA1 | P00915 | 2/20 | 0.45 |
| ▸ | CA2 | P00918 | 2/20 | 0.45 |
| ▸ | CA9 | Q16790 | 2/20 | 0.45 |
| ▸ | HPGD | P15428 | 1/20 | 0.45 |
| ▸ | L3MBTL1 | Q9Y468 | 1/20 | 0.45 |
| ▸ | MEN1 | O00255 | 5/20 | 0.43 |
| ▸ | KMT2A | Q03164 | 5/20 | 0.43 |
Click a target to see other patent compounds predicted against it — the reverse direction, in place.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| SCHEMBL483417 | 0.86 | GAA (0.46) | KDM4EGAAALDH1A1NPC1RAB9A | |
| SCHEMBL11011942 | 0.86 | GAA (0.48) | KDM4EGAAALDH1A1SMN1; SMN2GLA | |
| SCHEMBL3048096 | 0.84 | ALDH1A1 (0.55) | ALDH1A1NPC1RAB9ASMN1; SMN2CYP1A2 | |
| SCHEMBL4862187 | 0.83 | L3MBTL1 (0.54) | KDM4EGAAALDH1A1SMN1; SMN2GLA | |
| SCHEMBL11225958 | 0.83 | RAB9A (0.62) | KDM4EGAANPC1RAB9ASMN1; SMN2 | |
| SCHEMBL13132543 | 0.83 | NPC1 (0.57) | KDM4EGAAALDH1A1NPC1RAB9A | |
| SCHEMBL13132689 | 0.83 | NPC1 (0.57) | KDM4EGAAALDH1A1NPC1RAB9A | |
| SCHEMBL5287605 | 0.82 | CFD (0.61) | KDM4EGAAALDH1A1SMN1; SMN2CA12 | |
| SCHEMBL28259226 | 0.81 | GAA (0.42) | KDM4EGAAALDH1A1NPC1RAB9A | |
| SCHEMBL1542594 | 0.80 | PDK1 (0.50) | NPC1RAB9AHSD17B10MEN1KMT2A |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 1 patent. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| WO-2008122667-A2 | UREYLENE DERIVATIVES | SCHOOL OF PHARMACY (GB) | 2008-10-16 | — | — | WO | disclosed |