Predicted protein targets (top 20)
| gene | UniProt | supporting neighbours | confidence | |
|---|---|---|---|---|
| ▸ | NR2E1 | Q9Y466 | 6/20 | 0.50 |
| ▸ | ADRB2 | P07550 | 9/20 | 0.46 |
| ▸ | ADRB1 | P08588 | 7/20 | 0.45 |
| ▸ | CYP2D6 | P10635 | 6/20 | 0.45 |
| ▸ | ADRB3 | P13945 | 5/20 | 0.45 |
| ▸ | SLC6A4 | P31645 | 4/20 | 0.45 |
| ▸ | HTR2B | P41595 | 4/20 | 0.45 |
| ▸ | HTR2A | P28223 | 4/20 | 0.45 |
| ▸ | SIGMAR1 | Q99720 | 4/20 | 0.45 |
| ▸ | CYP1A2 | P05177 | 4/20 | 0.45 |
| ▸ | HTR1A | P08908 | 3/20 | 0.45 |
| ▸ | ALDH1A1 | P00352 | 3/20 | 0.45 |
| ▸ | HTR2C | P28335 | 3/20 | 0.45 |
| ▸ | HTR6 | P50406 | 3/20 | 0.45 |
| ▸ | ADRA2C | P18825 | 2/20 | 0.45 |
| ▸ | SLC6A2 | P23975 | 2/20 | 0.45 |
| ▸ | OPRK1 | P41145 | 2/20 | 0.45 |
| ▸ | KCNH2 | Q12809 | 2/20 | 0.45 |
| ▸ | SCN1A | P35498 | 2/20 | 0.45 |
| ▸ | SLC10A1 | Q14973 | 2/20 | 0.45 |
Click a target to see other patent compounds predicted against it — the reverse direction, in place.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| Hydrochloric Acid SCHEMBL11734283 | 0.99 | NR2E1 (0.49) | NR2E1ADRB2ADRB1CYP2D6ADRB3 | |
| SCHEMBL11226386 | 0.84 | NR2E1 (0.71) | NR2E1ADRB2ADRB1CYP2D6ADRB3 | |
| SCHEMBL11239573 | 0.83 | MEN1 (0.45) | ADRB2ADRB1CYP2D6ADRB3SLC6A4 | |
| Hydrochloric Acid SCHEMBL11229212 | 0.82 | MEN1 (0.46) | ADRB2ADRB1CYP2D6ADRB3SLC6A4 | |
| SCHEMBL11143175 | 0.82 | ADRB2 (0.69) | ADRB2ADRB1CYP2D6ADRB3SLC6A4 | |
| SCHEMBL11233401 | 0.80 | ALOX5 (0.51) | ADRB2ADRB1CYP2D6ADRB3SLC6A4 | |
| Hydrochloric Acid SCHEMBL11227660 | 0.79 | ALOX5 (0.50) | ADRB2ADRB1CYP2D6ADRB3SLC6A4 | |
| SCHEMBL11227323 | 0.77 | ADRB2 (0.69) | NR2E1ADRB2ADRB1CYP2D6ADRB3 | |
| SCHEMBL14461987 | 0.77 | NR2E1 (0.56) | NR2E1ADRB2ADRB1CYP2D6ADRB3 | |
| Hydrochloric Acid SCHEMBL11234328 | 0.76 | ADRB2 (0.70) | NR2E1ADRB2ADRB1CYP2D6ADRB3 |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 2 patents. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| US-4360464-A | Process for production of 1-aryloxy-aminopropane derivatives | TEIKOKU HORMONE MFG. CO. LTD. (JP) | 1982-11-23 | — | — | US | disclosed |
| US-4018824-A | ANTIULCER AND ADRENERGIC BLOCKING AGENTS | TEIKOKU HORMONE MFG. CO., LTD. (JA) | 1977-04-19 | — | — | US | disclosed |