Predicted protein targets (top 20)
| gene | UniProt | supporting neighbours | confidence | |
|---|---|---|---|---|
| ▸ | ALOX5 | P09917 | 1/20 | 0.51 |
| ▸ | CASR | P41180 | 7/20 | 0.47 |
| ▸ | CYP2D6 | P10635 | 2/20 | 0.45 |
| ▸ | ADRB2 | P07550 | 1/20 | 0.45 |
| ▸ | ADRB1 | P08588 | 1/20 | 0.45 |
| ▸ | ADRB3 | P13945 | 1/20 | 0.45 |
| ▸ | KDM1A | O60341 | 1/20 | 0.42 |
| ▸ | PPARG | P37231 | 2/20 | 0.41 |
| ▸ | MEN1 | O00255 | 2/20 | 0.41 |
| ▸ | KMT2A | Q03164 | 2/20 | 0.41 |
| ▸ | ITGB3 | P05106 | 1/20 | 0.41 |
| ▸ | ITGA2B | P08514 | 1/20 | 0.41 |
| ▸ | POLB | P06746 | 1/20 | 0.41 |
| ▸ | NCOA2 | Q15596 | 1/20 | 0.41 |
| ▸ | NCOA1 | Q15788 | 1/20 | 0.41 |
| ▸ | NCOA3 | Q9Y6Q9 | 1/20 | 0.41 |
| ▸ | RAB9A | P51151 | 1/20 | 0.41 |
| ▸ | SLC6A2 | P23975 | 1/20 | 0.40 |
| ▸ | SLC6A4 | P31645 | 1/20 | 0.40 |
| ▸ | SLC6A3 | Q01959 | 1/20 | 0.40 |
Click a target to see other patent compounds predicted against it — the reverse direction, in place.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| Hydrochloric Acid SCHEMBL11227660 | 0.99 | ALOX5 (0.50) | ALOX5CASRCYP2D6ADRB2ADRB1 | |
| SCHEMBL11239360 | 0.84 | ALOX5 (0.52) | ALOX5CASRCYP2D6ADRB2ADRB1 | |
| SCHEMBL11226228 | 0.80 | NR2E1 (0.50) | CYP2D6ADRB2ADRB1ADRB3MEN1 | |
| Hydrochloric Acid SCHEMBL11734283 | 0.79 | NR2E1 (0.49) | CYP2D6ADRB2ADRB1ADRB3MEN1 | |
| SCHEMBL11237234 | 0.77 | CYP2D6 (0.71) | CASRCYP2D6ADRB2ADRB1KDM1A | |
| SCHEMBL11239573 | 0.75 | MEN1 (0.45) | CYP2D6ADRB2ADRB1ADRB3MEN1 | |
| Hydrochloric Acid SCHEMBL11229212 | 0.74 | MEN1 (0.46) | CYP2D6ADRB2ADRB1ADRB3MEN1 | |
| SCHEMBL11143175 | 0.71 | ADRB2 (0.69) | CYP2D6ADRB2ADRB1ADRB3MEN1 | |
| SCHEMBL12085980 | 0.71 | ADRB2 (0.46) | CYP2D6ADRB2ADRB1ADRB3KMT2A | |
| SCHEMBL51460 | 0.70 | ALOX5 (1.00) | ALOX5PPARGMEN1KMT2APOLB |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 2 patents. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| US-4360464-A | Process for production of 1-aryloxy-aminopropane derivatives | TEIKOKU HORMONE MFG. CO. LTD. (JP) | 1982-11-23 | — | — | US | disclosed |
| US-4018824-A | ANTIULCER AND ADRENERGIC BLOCKING AGENTS | TEIKOKU HORMONE MFG. CO., LTD. (JA) | 1977-04-19 | — | — | US | disclosed |