SCHEMBL1122632

Similar compounds — the chemically nearest patent molecules

Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.

	Compound	similarity	top predicted	shared targets
	SCHEMBL1123333	0.91	GPR132 (0.67)	PPARGGPR132PTPN1ITGB3ITGA2B
	SCHEMBL1123055	0.88	GAA (0.80)	GAARAB9APPARGGPR132ERAP2
	SCHEMBL1123019	0.88	GAA (0.62)	GAARAB9APPARGGPR132ERAP2
	SCHEMBL1122610	0.86	RAB9A (0.74)	GAARAB9APPARGGPR132ERAP2
	SCHEMBL27638047	0.86	RAB9A (0.74)	GAARAB9APPARGGPR132ERAP2
	SCHEMBL1123147	0.86	GAA (0.71)	GAARAB9APPARGGPR132ERAP2
	SCHEMBL1122748	0.85	GAA (0.59)	GAARAB9APPARGGPR132ERAP2
	SCHEMBL1122645	0.85	GAA (0.69)	GAARAB9APPARGGPR132ERAP2
	SCHEMBL27658965	0.85	GAA (0.69)	GAARAB9APPARGGPR132ERAP2
	SCHEMBL1122834	0.85	GAA (0.75)	GAARAB9APPARGGPR132ERAP2

Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.

Patent provenance — the patents this molecule appears in, and who filed them

Claimed or disclosed in 8 patents. claimed = in the patent's claims; disclosed = body only.

Patent text — is the patent's own abstract consistent with the prediction?

For each of this compound's patents that has machine-readable text (1 of them — usually the abstract, not the full specification), we ask MedCPT which protein the text reads most about, and where the chemistry-predicted target lands among 4885 human targets. A high rank means the patent's own wording is consistent with the prediction — a weak, independent signal, not proof of activity.

“Text reads most about” is the patent abstract's nearest protein in MedCPT space (background-debiased). Only ~1.4% of patents have machine-readable text, so most compounds won't have this panel.