SCHEMBL11226437

SCHEMBL11226437

O=C(COC(=O)c1c(Cl)cccc1Cl)Nc1ccccc1

nearest known ligand 0.67

Predicted protein targets (top 16)

geneUniProtsupporting neighboursconfidence
L3MBTL1 Q9Y468 3/20 0.67
TDP1 Q9NUW8 1/20 0.67
KMT2A Q03164 5/20 0.59
ALDH1A1 P00352 4/20 0.59
RAB9A P51151 4/20 0.59
GAA P10253 2/20 0.59
THRB P10828 1/20 0.59
NPSR1 Q6W5P4 1/20 0.59
MEN1 O00255 3/20 0.56
MAPT P10636 3/20 0.55
SMN1; SMN2 Q16637 3/20 0.55
KLK7 P49862 1/20 0.54
TXNRD1 Q16881 1/20 0.53
NPC1 O15118 2/20 0.53
LMNA P02545 2/20 0.51
KDM4E B2RXH2 1/20 0.51

Click a target to see other patent compounds predicted against it — the reverse direction, in place.

Similar compounds — the chemically nearest patent molecules

Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.

Compoundsimilaritytop predictedshared targets
SCHEMBL10996044 0.79 ALDH1A1 (0.63) TDP1KMT2AALDH1A1GAANPSR1
SCHEMBL6801086 0.79 ALDH1A1 (0.63) L3MBTL1TDP1KMT2AALDH1A1RAB9A
SCHEMBL9710367 0.78 KMT2A (0.62) L3MBTL1TDP1KMT2AALDH1A1RAB9A
SCHEMBL11230083 0.77 KDM4E (0.57) L3MBTL1TDP1KMT2AALDH1A1RAB9A
SCHEMBL3764257 0.77 RAB9A (0.55) L3MBTL1TDP1KMT2AALDH1A1RAB9A
SCHEMBL11232113 0.76 RAB9A (0.56) L3MBTL1TDP1KMT2AALDH1A1RAB9A
SCHEMBL10600066 0.76 MAPT (0.53) L3MBTL1TDP1KMT2AALDH1A1RAB9A
SCHEMBL11927841 0.75 RAB9A (0.54) L3MBTL1TDP1KMT2AALDH1A1RAB9A
SCHEMBL11232066 0.74 L3MBTL1 (0.57) L3MBTL1TDP1KMT2AALDH1A1RAB9A
SCHEMBL31470170 0.74 MAPT (0.53) TDP1KMT2AALDH1A1RAB9AMEN1

Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.

Patent provenance — the patents this molecule appears in, and who filed them

Claimed or disclosed in 1 patent. claimed = in the patent's claims; disclosed = body only.

PatentTitleAssigneePublishedPriorityFilingCountryStatus
US-4309566-A RETARDATION OR STIMULATION OF GROWTH OF BROAD LEAF PLANTS FMC CORPORATION (US) 1982-01-05 US disclosed