Predicted protein targets (top 13)
| gene | UniProt | supporting neighbours | confidence | |
|---|---|---|---|---|
| ▸ | KMT2A | Q03164 | 5/20 | 0.62 |
| ▸ | POLB | P06746 | 3/20 | 0.56 |
| ▸ | MEN1 | O00255 | 4/20 | 0.56 |
| ▸ | LMNA | P02545 | 2/20 | 0.56 |
| ▸ | ALDH1A1 | P00352 | 2/20 | 0.56 |
| ▸ | NPC1 | O15118 | 9/20 | 0.55 |
| ▸ | RAB9A | P51151 | 7/20 | 0.55 |
| ▸ | NOTUM | Q6P988 | 2/20 | 0.55 |
| ▸ | TDP1 | Q9NUW8 | 1/20 | 0.55 |
| ▸ | SMN1; SMN2 | Q16637 | 3/20 | 0.54 |
| ▸ | HPGD | P15428 | 1/20 | 0.51 |
| ▸ | MAPK1 | P28482 | 1/20 | 0.51 |
| ▸ | L3MBTL1 | Q9Y468 | 1/20 | 0.51 |
Click a target to see other patent compounds predicted against it — the reverse direction, in place.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| SCHEMBL5638709 | 0.86 | KMT2A (0.70) | KMT2APOLBMEN1LMNANPC1 | |
| SCHEMBL25977944 | 0.84 | CYP1A2 (0.65) | KMT2AMEN1LMNAALDH1A1NPC1 | |
| SCHEMBL10726989 | 0.79 | NPSR1 (0.64) | KMT2APOLBMEN1LMNAALDH1A1 | |
| SCHEMBL27903404 | 0.79 | RAB9A (0.76) | KMT2AMEN1ALDH1A1RAB9ASMN1; SMN2 | |
| SCHEMBL9722714 | 0.79 | RAB9A (0.64) | KMT2APOLBMEN1LMNAALDH1A1 | |
| SCHEMBL11226437 | 0.78 | L3MBTL1 (0.67) | KMT2AMEN1LMNAALDH1A1NPC1 | |
| SCHEMBL11082064 | 0.78 | NOTUM (0.63) | KMT2APOLBMEN1LMNAALDH1A1 | |
| SCHEMBL4208290 | 0.78 | MEN1 (0.51) | KMT2APOLBMEN1ALDH1A1NPC1 | |
| SCHEMBL3498895 | 0.78 | LMNA (0.78) | KMT2AMEN1LMNAALDH1A1NPC1 | |
| SCHEMBL3729436 | 0.77 | KMT2A (1.00) | KMT2ALMNAALDH1A1TDP1HPGD |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 21 patents — showing the first 20. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| CN-114516813-B | Continuous flow preparation method of diclofenac sodium | 复旦大学 | 2024-05-28 | — | — | CN | claimed |
| US-11905229-B2 | Method for synthesizing diclofenac sodium | FUDAN UNIVERSITY (CN) | 2024-02-20 | — | — | US | claimed |
| US-11834388-B2 | Continuous-flow preparation method of diclofenac sodium | FUDAN UNIVERSITY (CN) | 2023-12-05 | — | — | US | claimed |
| CN-114539086-B | Synthesis method of diclofenac sodium | 复旦大学 | 2023-10-03 | — | — | CN | claimed |
| US-20230234911-A1 | METHOD FOR SYNTHESIZING DICLOFENAC SODIUM | FUDAN UNIVERSITY (CN) | 2023-07-27 | — | — | US | claimed |
| US-20230192595-A1 | CONTINUOUS-FLOW PREPARATION METHOD OF DICLOFENAC SODIUM | FUDAN UNIVERSITY (CN) | 2023-06-22 | — | — | US | claimed |
| CN-114539086-A | Method for synthesizing diclofenac sodium | 复旦大学 | 2022-05-27 | — | — | CN | claimed |
| CN-114516813-A | Continuous flow preparation method of diclofenac sodium | 复旦大学 | 2022-05-20 | — | — | CN | claimed |
| CN-114516813-B | Continuous flow preparation method of diclofenac sodium | 复旦大学 | 2024-05-28 | — | — | CN | disclosed |
| US-11905229-B2 | Method for synthesizing diclofenac sodium | FUDAN UNIVERSITY (CN) | 2024-02-20 | — | — | US | disclosed |
| US-11905229-B2 | Method for synthesizing diclofenac sodium | FUDAN UNIVERSITY (CN) | 2024-02-20 | — | — | US | disclosed |
| US-11834388-B2 | Continuous-flow preparation method of diclofenac sodium | FUDAN UNIVERSITY (CN) | 2023-12-05 | — | — | US | disclosed |
| CN-114539086-B | Synthesis method of diclofenac sodium | 复旦大学 | 2023-10-03 | — | — | CN | disclosed |
| US-20230234911-A1 | METHOD FOR SYNTHESIZING DICLOFENAC SODIUM | FUDAN UNIVERSITY (CN) | 2023-07-27 | — | — | US | disclosed |
| US-20230192595-A1 | CONTINUOUS-FLOW PREPARATION METHOD OF DICLOFENAC SODIUM | FUDAN UNIVERSITY (CN) | 2023-06-22 | — | — | US | disclosed |
| CN-114539086-A | Method for synthesizing diclofenac sodium | 复旦大学 | 2022-05-27 | — | — | CN | disclosed |
| CN-114516813-A | Continuous flow preparation method of diclofenac sodium | 复旦大学 | 2022-05-20 | — | — | CN | disclosed |
| CN-103113236-A | Preparation method of 2,6-dichlorodiphenylamine | HENAN DONGTAI PHARM CO LTD | 2013-05-22 | — | — | CN | disclosed |
| WO-1992022522-A1 | A PROCESS FOR THE PREPARATION OF N-(2,6-DICHLOROPHENYL)-N-PHENYL-N-(CHLOROACETYL)-AMINE | LABORATORIO CHIMICO INTERNAZIONALE S.P.A. (IT) | 1992-12-23 | — | — | WO | disclosed |
| WO-1992022522-A1 | A PROCESS FOR THE PREPARATION OF N-(2,6-DICHLOROPHENYL)-N-PHENYL-N-(CHLOROACETYL)-AMINE | LABORATORIO CHIMICO INTERNAZIONALE S.P.A. (IT) | 1992-12-23 | — | — | WO | disclosed |
Patent text — is the patent's own abstract consistent with the prediction?
For each of this compound's patents that has machine-readable text (4 of them — usually the abstract, not the full specification), we ask MedCPT which protein the text reads most about, and where the chemistry-predicted target lands among 4885 human targets. A high rank means the patent's own wording is consistent with the prediction — a weak, independent signal, not proof of activity.
| Patent | Title | Text reads most about | Predicted target · text-rank |
|---|---|---|---|
| US-11905229-B2 | Method for synthesizing diclofenac sodium | SULT2A1, CRYAA, AADAC | KMT2A 1494/4885POLB 2377/4885MEN1 4422/4885 |
| US-20230234911-A1 | METHOD FOR SYNTHESIZING DICLOFENAC SODIUM | SULT2A1, CRYAA, AADAC | KMT2A 1494/4885POLB 2377/4885MEN1 4422/4885 |
| US-20230192595-A1 | CONTINUOUS-FLOW PREPARATION METHOD OF DICLOFENAC SODIUM | SULT2A1, NIT2, CA2 | KMT2A 1210/4885POLB 3467/4885MEN1 4501/4885 |
| US-11834388-B2 | Continuous-flow preparation method of diclofenac sodium | SULT2A1, NIT2, CA2 | KMT2A 1097/4885POLB 3453/4885MEN1 4476/4885 |
“Text reads most about” is the patent abstract's nearest protein in MedCPT space (background-debiased). Only ~1.4% of patents have machine-readable text, so most compounds won't have this panel.