Predicted protein targets (top 9)
| gene | UniProt | supporting neighbours | confidence | |
|---|---|---|---|---|
| ▸ | DRD3 | P35462 | 5/20 | 0.46 |
| ▸ | DRD4 | P21917 | 4/20 | 0.46 |
| ▸ | DRD2 | P14416 | 3/20 | 0.46 |
| ▸ | MAPT | P10636 | 5/20 | 0.44 |
| ▸ | KDM4E | B2RXH2 | 1/20 | 0.43 |
| ▸ | ATM | Q13315 | 1/20 | 0.43 |
| ▸ | SMN1; SMN2 | Q16637 | 1/20 | 0.42 |
| ▸ | HTR6 | P50406 | 1/20 | 0.41 |
| ▸ | TP53 | P04637 | 1/20 | 0.40 |
Click a target to see other patent compounds predicted against it — the reverse direction, in place.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| SCHEMBL11131906 | 0.83 | ADRB1 (0.37) | DRD3DRD4DRD2HTR6 | |
| SCHEMBL7943354 | 0.73 | DRD3 (0.58) | DRD3DRD4DRD2MAPTKDM4E | |
| SCHEMBL10994724 | 0.73 | OPRM1 (0.48) | DRD4SMN1; SMN2 | |
| Hydrochloric Acid SCHEMBL11221310 | 0.72 | CYP2D6 (0.51) | DRD3DRD4DRD2MAPTKDM4E | |
| SCHEMBL7859854 | 0.72 | SLC6A4 (0.54) | DRD3DRD4DRD2MAPTTP53 | |
| SCHEMBL24729172 | 0.71 | MGAM (0.44) | MAPTKDM4EATMTP53 | |
| SCHEMBL16510074 | 0.71 | OPRM1 (0.53) | DRD4 | |
| SCHEMBL29651245 | 0.71 | MGAM (0.44) | MAPTKDM4EATMTP53 | |
| SCHEMBL1413413 | 0.68 | CYP2D6 (0.46) | DRD3DRD4DRD2MAPTKDM4E | |
| SCHEMBL22864444 | 0.68 | ATM (0.48) | DRD3DRD4DRD2MAPTKDM4E |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 1 patent. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| US-4332808-A | Dopaminergically stimulating 4-substituted indoles | ROUSSEL UCLAF (FR) | 1982-06-01 | — | — | US | disclosed |