Predicted protein targets (top 20)
| gene | UniProt | supporting neighbours | confidence | |
|---|---|---|---|---|
| ▸ | PTGS2 | P35354 | 3/20 | 0.51 |
| ▸ | PTGS1 | P23219 | 1/20 | 0.51 |
| ▸ | ALDH1A1 | P00352 | 4/20 | 0.48 |
| ▸ | LMNA | P02545 | 3/20 | 0.48 |
| ▸ | POLB | P06746 | 1/20 | 0.46 |
| ▸ | TLR9 | Q9NR96 | 2/20 | 0.45 |
| ▸ | CYP19A1 | P11511 | 1/20 | 0.44 |
| ▸ | CA1 | P00915 | 1/20 | 0.43 |
| ▸ | CA2 | P00918 | 1/20 | 0.43 |
| ▸ | MEN1 | O00255 | 3/20 | 0.43 |
| ▸ | KMT2A | Q03164 | 3/20 | 0.43 |
| ▸ | TDP1 | Q9NUW8 | 2/20 | 0.43 |
| ▸ | PLAU | P00749 | 1/20 | 0.43 |
| ▸ | RAB9A | P51151 | 2/20 | 0.41 |
| ▸ | MAPT | P10636 | 3/20 | 0.41 |
| ▸ | SMN1; SMN2 | Q16637 | 2/20 | 0.41 |
| ▸ | MAPK1 | P28482 | 2/20 | 0.41 |
| ▸ | L3MBTL1 | Q9Y468 | 2/20 | 0.41 |
| ▸ | NPC1 | O15118 | 1/20 | 0.41 |
| ▸ | HTT | P42858 | 1/20 | 0.41 |
Click a target to see other patent compounds predicted against it — the reverse direction, in place.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| SCHEMBL2212619 | 0.86 | TUBB4A (0.48) | ALDH1A1LMNAPOLBCYP19A1MEN1 | |
| SCHEMBL2212628 | 0.86 | TUBB4A (0.48) | ALDH1A1LMNAPOLBCYP19A1MEN1 | |
| SCHEMBL1122446 | 0.86 | ALDH1A1 (0.63) | ALDH1A1LMNACYP19A1CA1CA2 | |
| SCHEMBL1634604 | 0.85 | MAPT (0.46) | ALDH1A1LMNAPOLBMEN1KMT2A | |
| SCHEMBL1634600 | 0.85 | MAPT (0.46) | ALDH1A1LMNAPOLBMEN1KMT2A | |
| SCHEMBL2212726 | 0.84 | MEN1 (0.56) | ALDH1A1LMNAPOLBMEN1KMT2A | |
| SCHEMBL2212730 | 0.84 | MEN1 (0.56) | ALDH1A1LMNAPOLBMEN1KMT2A | |
| SCHEMBL1122684 | 0.82 | LMNA (0.54) | PTGS2ALDH1A1LMNACA1CA2 | |
| SCHEMBL1122313 | 0.82 | ALDH1A1 (0.52) | PTGS2PTGS1ALDH1A1LMNAMEN1 | |
| SCHEMBL1122699 | 0.82 | MAOA (0.53) | ALDH1A1LMNAMEN1KMT2AMAPT |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 2 patents. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| EP-1379508-B9 | N-(ARYL)-2-ARYLETHENESULFONAMIDES AND THERAPEUTIC USES THEREOF | UNIV TEMPLE (US) | 2011-02-09 | — | — | EP | disclosed |
| EP-1379508-B1 | N-(ARYL)-2-ARYLETHENESULFONAMIDES AND THERAPEUTIC USES THEREOF | UNIV TEMPLE (US) | 2010-09-01 | — | — | EP | disclosed |