SCHEMBL11227271

SCHEMBL11227271

CC(CN)NCC(C)C(=O)OC(C)C

nearest known ligand 0.32

Predicted protein targets (top 9)

geneUniProtsupporting neighboursconfidence
TSHR P16473 1/20 0.32
CA12 O43570 2/20 0.32
CA1 P00915 2/20 0.32
CA2 P00918 2/20 0.32
CA9 Q16790 2/20 0.32
CA7 P43166 1/20 0.32
CA14 Q9ULX7 1/20 0.32
CYP4F2 P78329 1/20 0.31
CYP4A11 Q02928 1/20 0.31

Click a target to see other patent compounds predicted against it — the reverse direction, in place.

Similar compounds — the chemically nearest patent molecules

Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.

Compoundsimilaritytop predictedshared targets
SCHEMBL11227939 0.85 SMN1; SMN2 (0.34) CA12CA9CA7CA14
SCHEMBL11230401 0.81 CPB2 (0.37) CA12CA1CA2CA9
SCHEMBL11222761 0.79 LMNA (0.33) TSHR
SCHEMBL11233354 0.78 CA12 (0.33) TSHRCA12CA1CA2CA9
SCHEMBL6437107 0.78 TSHR (0.42) TSHRCA12CA1CA2CA9
SCHEMBL18502989 0.78 TSHR (0.42) TSHRCA12CA1CA2CA9
SCHEMBL18502991 0.78 TSHR (0.42) TSHRCA12CA1CA2CA9
SCHEMBL11238256 0.76 ALDH1A1 (0.40) TSHR
Hydrochloric Acid SCHEMBL19603131 0.76 TSHR (0.40) TSHRCA12CA1CA2CA9
Hydrochloric Acid SCHEMBL19603120 0.76 TSHR (0.40) TSHRCA12CA1CA2CA9

Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.

Patent provenance — the patents this molecule appears in, and who filed them

Claimed or disclosed in 2 patents. claimed = in the patent's claims; disclosed = body only.

PatentTitleAssigneePublishedPriorityFilingCountryStatus
US-4315846-A FUNGICIDES TOKYO ORGANIC CHEMICAL INDUSTRIES, LTD. (JP) 1982-02-16 US disclosed
EP-0037861-A1 Salts of alkylenebisdithiocarbamic acid derivatives, processes for their preparation, fungicidal compositions containing them and methods of combating fungi TOKYO ORGANIC CHEMICAL INDUSTRIES, LTD. (JP) 1981-10-21 EP disclosed