SCHEMBL11230401

SCHEMBL11230401

CCOC(=O)C(C)CNC(C)CN

nearest known ligand 0.42

Predicted protein targets (top 20)

geneUniProtsupporting neighboursconfidence
CPB2 Q96IY4 1/20 0.37
GAA P10253 2/20 0.35
ALOX15 P16050 1/20 0.35
MGAM O43451 1/20 0.35
SI P14410 1/20 0.35
MGAM2 Q2M2H8 1/20 0.35
ALDH1A1 P00352 3/20 0.35
HPGD P15428 1/20 0.35
MMP8 P22894 3/20 0.34
CAD P27708 1/20 0.34
CYP3A4 P08684 1/20 0.34
CYP2C19 P33261 1/20 0.34
CYP1A2 P05177 1/20 0.33
CA12 O43570 1/20 0.33
CA1 P00915 1/20 0.33
CA2 P00918 1/20 0.33
CA9 Q16790 1/20 0.33
LMNA P02545 1/20 0.32
HSD17B10 Q99714 1/20 0.32
METAP2 P50579 3/20 0.32

Click a target to see other patent compounds predicted against it — the reverse direction, in place.

Similar compounds — the chemically nearest patent molecules

Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.

Compoundsimilaritytop predictedshared targets
SCHEMBL11222761 0.86 LMNA (0.33) ALDH1A1LMNA
SCHEMBL26529433 0.85 GAA (0.38) GAAALOX15MGAMSIMGAM2
SCHEMBL11227939 0.85 SMN1; SMN2 (0.34) CA12CA9
SCHEMBL11238256 0.83 ALDH1A1 (0.40) ALDH1A1HPGDCYP3A4CYP2C19CYP1A2
SCHEMBL11227271 0.81 TSHR (0.32) CA12CA1CA2CA9
SCHEMBL26529043 0.80 GAA (0.41) GAAALOX15MGAMSIMGAM2
SCHEMBL21193040 0.79 KMT2A (0.35) GAAMGAMSIMGAM2ALDH1A1
SCHEMBL335271 0.78
SCHEMBL7391309 0.78
SCHEMBL26529039 0.77 GAA (0.38) GAAALOX15MGAMSIMGAM2

Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.

Patent provenance — the patents this molecule appears in, and who filed them

Claimed or disclosed in 2 patents. claimed = in the patent's claims; disclosed = body only.

PatentTitleAssigneePublishedPriorityFilingCountryStatus
US-4315846-A FUNGICIDES TOKYO ORGANIC CHEMICAL INDUSTRIES, LTD. (JP) 1982-02-16 US disclosed
EP-0037861-A1 Salts of alkylenebisdithiocarbamic acid derivatives, processes for their preparation, fungicidal compositions containing them and methods of combating fungi TOKYO ORGANIC CHEMICAL INDUSTRIES, LTD. (JP) 1981-10-21 EP disclosed