Predicted protein targets (top 20)
| gene | UniProt | supporting neighbours | confidence | |
|---|---|---|---|---|
| ▸ | KDM4E | B2RXH2 | 5/20 | 0.62 |
| ▸ | ALDH1A1 | P00352 | 2/20 | 0.62 |
| ▸ | MMP2 | P08253 | 7/20 | 0.60 |
| ▸ | KMT2A | Q03164 | 3/20 | 0.55 |
| ▸ | MEN1 | O00255 | 2/20 | 0.52 |
| ▸ | SMN1; SMN2 | Q16637 | 1/20 | 0.52 |
| ▸ | BRD4 | O60885 | 1/20 | 0.49 |
| ▸ | CYP3A4 | P08684 | 2/20 | 0.49 |
| ▸ | CYP2C19 | P33261 | 2/20 | 0.49 |
| ▸ | POLB | P06746 | 2/20 | 0.49 |
| ▸ | CYP1A2 | P05177 | 1/20 | 0.49 |
| ▸ | CYP2D6 | P10635 | 1/20 | 0.49 |
| ▸ | HPGD | P15428 | 1/20 | 0.49 |
| ▸ | ATM | Q13315 | 1/20 | 0.49 |
| ▸ | L3MBTL1 | Q9Y468 | 1/20 | 0.49 |
| ▸ | NPC1 | O15118 | 1/20 | 0.48 |
| ▸ | RAB9A | P51151 | 1/20 | 0.48 |
| ▸ | MAPT | P10636 | 1/20 | 0.48 |
| ▸ | CYP2C9 | P11712 | 1/20 | 0.48 |
| ▸ | HTT | P42858 | 1/20 | 0.48 |
Click a target to see other patent compounds predicted against it — the reverse direction, in place.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| SCHEMBL21788585 | 0.84 | MMP2 (0.60) | KDM4EALDH1A1MMP2KMT2AMEN1 | |
| SCHEMBL979684 | 0.82 | KDM4E (0.69) | KDM4EALDH1A1MMP2KMT2AMEN1 | |
| SCHEMBL5547053 | 0.81 | KDM4E (0.49) | KDM4EALDH1A1KMT2AMEN1CYP3A4 | |
| SCHEMBL9318480 | 0.81 | TLR8 (0.63) | KDM4EALDH1A1MMP2SMN1; SMN2CYP2C19 | |
| SCHEMBL27799043 | 0.80 | KDM4E (0.61) | KDM4EALDH1A1MMP2KMT2AMEN1 | |
| SCHEMBL1520226 | 0.80 | KMT2A (0.62) | ALDH1A1KMT2ASMN1; SMN2NPC1RAB9A | |
| SCHEMBL27799061 | 0.80 | KDM4E (0.72) | KDM4EALDH1A1MMP2KMT2AMEN1 | |
| SCHEMBL9318535 | 0.80 | ALDH1A1 (0.60) | KDM4EALDH1A1MMP2KMT2ASMN1; SMN2 | |
| SCHEMBL1963617 | 0.79 | CFTR (0.68) | KDM4EALDH1A1KMT2AMEN1CYP3A4 | |
| SCHEMBL5717623 | 0.79 | ALDH1A1 (0.67) | KDM4EALDH1A1KMT2AMEN1SMN1; SMN2 |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 6 patents. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| EP-1644321-B1 | NEW BENZAMIDES AS PPATY MODULATORS | S A L V A T LAB SA (ES) | 2011-02-09 | — | — | EP | disclosed |
| EP-1644321-A2 | NEW BENZAMIDES AS PPATY MODULATORS | LABORATORIOS S.A.L.V.A.T., S.A. (ES) | 2006-04-12 | — | — | EP | disclosed |
| WO-2004110983-A2 | NEW BENZAMIDES AS PPARϒ MODULATORS | LABORATORIOS S.A.L.V.A.T., S.A. (ES) | 2004-12-23 | — | — | WO | disclosed |
| EP-0304322-B1 | 1-SUBSTITUTED ALKYL-2-OXO-1,2-DIHYDROQUINOXALINE DERIVATIVES | ASAHI KASEI KOGYO KABUSHIKI KAISHA (JP) | 1992-12-02 | — | — | EP | disclosed |
| US-4870171-A | HYPOTENSIVE | TOYO JOZO KABUSHIKI KAISHA (JP) | 1989-09-26 | — | — | US | disclosed |
| EP-0304322-A1 | 1-Substituted alkyl-2-oxo-1,2-dihydroquinoxaline derivatives | ASAHI KASEI KOGYO KABUSHIKI KAISHA (JP) | 1989-02-22 | — | — | EP | disclosed |