Predicted protein targets (top 19)
| gene | UniProt | supporting neighbours | confidence | |
|---|---|---|---|---|
| ▸ | KDM4E | B2RXH2 | 6/20 | 0.61 |
| ▸ | ALDH1A1 | P00352 | 2/20 | 0.61 |
| ▸ | MMP2 | P08253 | 8/20 | 0.56 |
| ▸ | ATM | Q13315 | 1/20 | 0.52 |
| ▸ | L3MBTL1 | Q9Y468 | 1/20 | 0.52 |
| ▸ | KMT2A | Q03164 | 2/20 | 0.52 |
| ▸ | HRH1 | P35367 | 1/20 | 0.52 |
| ▸ | MAPK1 | P28482 | 2/20 | 0.51 |
| ▸ | POLB | P06746 | 1/20 | 0.51 |
| ▸ | LMNA | P02545 | 1/20 | 0.50 |
| ▸ | PKM | P14618 | 1/20 | 0.50 |
| ▸ | NPSR1 | Q6W5P4 | 1/20 | 0.50 |
| ▸ | MEN1 | O00255 | 1/20 | 0.49 |
| ▸ | SMN1; SMN2 | Q16637 | 1/20 | 0.49 |
| ▸ | NPC1 | O15118 | 1/20 | 0.48 |
| ▸ | RAB9A | P51151 | 1/20 | 0.48 |
| ▸ | CASP1 | P29466 | 1/20 | 0.48 |
| ▸ | CASP7 | P55210 | 1/20 | 0.48 |
| ▸ | HSD17B10 | Q99714 | 1/20 | 0.47 |
Click a target to see other patent compounds predicted against it — the reverse direction, in place.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| SCHEMBL13587967 | 0.85 | LMNA (0.57) | KDM4EALDH1A1HRH1LMNAPKM | |
| SCHEMBL501463 | 0.82 | HPGD (0.69) | KDM4EALDH1A1HRH1POLBLMNA | |
| SCHEMBL1122732 | 0.80 | KDM4E (0.62) | KDM4EALDH1A1MMP2ATML3MBTL1 | |
| SCHEMBL9318535 | 0.78 | ALDH1A1 (0.60) | KDM4EALDH1A1MMP2ATML3MBTL1 | |
| SCHEMBL5936613 | 0.78 | PIN1 (0.60) | KDM4EALDH1A1MMP2HRH1MAPK1 | |
| SCHEMBL21788585 | 0.77 | MMP2 (0.60) | KDM4EALDH1A1MMP2ATML3MBTL1 | |
| SCHEMBL28512227 | 0.77 | KDM4E (0.64) | KDM4EALDH1A1KMT2AHRH1MAPK1 | |
| SCHEMBL28287010 | 0.77 | KDM4E (0.78) | KDM4EALDH1A1MMP2KMT2AMAPK1 | |
| SCHEMBL3829770 | 0.76 | TSHR (0.64) | KDM4EALDH1A1ATML3MBTL1KMT2A | |
| SCHEMBL27799061 | 0.76 | KDM4E (0.72) | KDM4EALDH1A1MMP2KMT2AMEN1 |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 3 patents. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| CN-101701032-B | Quinoxalinone low molecular weight peptide derivative with matrix metalloproteinases inhibition function and preparation method and application thereof | UNIV SHANDONG | 2014-05-07 | — | — | CN | disclosed |
| CN-101704792-A | Quinoxalinone derivative with matrix metalloproteinase inhibitory activity and preparation method and application thereof | UNIV SHANDONG | 2010-05-12 | — | — | CN | disclosed |
| CN-101701032-A | Quinoxalinone low molecular weight peptide derivative with matrix metalloproteinases inhibition function and preparation method and application thereof | UNIV SHANDONG | 2010-05-05 | — | — | CN | disclosed |