Predicted protein targets (top 19)
| gene | UniProt | supporting neighbours | confidence | |
|---|---|---|---|---|
| ▸ | TP53 | P04637 | 2/20 | 0.52 |
| ▸ | MAPT | P10636 | 2/20 | 0.52 |
| ▸ | NPC1 | O15118 | 1/20 | 0.52 |
| ▸ | ALDH1A1 | P00352 | 1/20 | 0.52 |
| ▸ | RAB9A | P51151 | 1/20 | 0.52 |
| ▸ | BACE1 | P56817 | 1/20 | 0.52 |
| ▸ | SMN1; SMN2 | Q16637 | 1/20 | 0.52 |
| ▸ | CTSL | P07711 | 1/20 | 0.48 |
| ▸ | CTSB | P07858 | 1/20 | 0.48 |
| ▸ | CTSK | P43235 | 1/20 | 0.48 |
| ▸ | ACACB | O00763 | 9/20 | 0.46 |
| ▸ | POLB | P06746 | 2/20 | 0.46 |
| ▸ | LMNA | P02545 | 1/20 | 0.46 |
| ▸ | NAAA | Q02083 | 1/20 | 0.45 |
| ▸ | MEN1 | O00255 | 1/20 | 0.43 |
| ▸ | KMT2A | Q03164 | 1/20 | 0.43 |
| ▸ | LTA4H | P09960 | 1/20 | 0.42 |
| ▸ | PKM | P14618 | 1/20 | 0.42 |
| ▸ | MAPK1 | P28482 | 1/20 | 0.42 |
Click a target to see other patent compounds predicted against it — the reverse direction, in place.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| SCHEMBL11225338 | 0.79 | NAAA (0.47) | TP53MAPTNPC1ALDH1A1RAB9A | |
| SCHEMBL11230944 | 0.77 | NAAA (0.45) | TP53MAPTNPC1ALDH1A1RAB9A | |
| SCHEMBL9965812 | 0.75 | CTSL (0.62) | CTSLCTSBCTSKNAAA | |
| SCHEMBL20875967 | 0.75 | MAOB (0.54) | MAPTNPC1RAB9ASMN1; SMN2LMNA | |
| SCHEMBL11232830 | 0.74 | NAAA (0.43) | MAPTNPC1ALDH1A1RAB9ASMN1; SMN2 | |
| SCHEMBL11227595 | 0.74 | NAAA (0.43) | MAPTNPC1ALDH1A1RAB9ASMN1; SMN2 | |
| SCHEMBL11293541 | 0.73 | LMNA (0.67) | TP53MAPTRAB9ASMN1; SMN2LMNA | |
| SCHEMBL11229024 | 0.72 | CTSL (0.58) | TP53NPC1ALDH1A1SMN1; SMN2CTSL | |
| SCHEMBL21667797 | 0.70 | BPTF (0.61) | MAPTNPC1RAB9ASMN1; SMN2LMNA | |
| SCHEMBL18361624 | 0.70 | OPRM1 (0.57) | CTSLCTSBCTSKNAAA |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 2 patents. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| US-4360464-A | Process for production of 1-aryloxy-aminopropane derivatives | TEIKOKU HORMONE MFG. CO. LTD. (JP) | 1982-11-23 | — | — | US | claimed |
| US-4360464-A | Process for production of 1-aryloxy-aminopropane derivatives | TEIKOKU HORMONE MFG. CO. LTD. (JP) | 1982-11-23 | — | — | US | disclosed |