Predicted protein targets (top 20)
| gene | UniProt | supporting neighbours | confidence | |
|---|---|---|---|---|
| ▸ | LMNA | P02545 | 4/20 | 0.64 |
| ▸ | ALDH1A1 | P00352 | 3/20 | 0.57 |
| ▸ | SMN1; SMN2 | Q16637 | 3/20 | 0.57 |
| ▸ | RAB9A | P51151 | 1/20 | 0.57 |
| ▸ | TP53 | P04637 | 2/20 | 0.54 |
| ▸ | AR | P10275 | 1/20 | 0.54 |
| ▸ | TSHR | P16473 | 1/20 | 0.54 |
| ▸ | HTT | P42858 | 1/20 | 0.53 |
| ▸ | CA12 | O43570 | 1/20 | 0.52 |
| ▸ | CA1 | P00915 | 1/20 | 0.52 |
| ▸ | CA2 | P00918 | 1/20 | 0.52 |
| ▸ | CA7 | P43166 | 1/20 | 0.52 |
| ▸ | CA9 | Q16790 | 1/20 | 0.52 |
| ▸ | CA14 | Q9ULX7 | 1/20 | 0.52 |
| ▸ | MEN1 | O00255 | 3/20 | 0.51 |
| ▸ | KMT2A | Q03164 | 3/20 | 0.51 |
| ▸ | HPGD | P15428 | 1/20 | 0.51 |
| ▸ | PRKCZ | Q05513 | 1/20 | 0.51 |
| ▸ | PTGS1 | P23219 | 1/20 | 0.51 |
| ▸ | GABRA1 | P14867 | 1/20 | 0.50 |
Click a target to see other patent compounds predicted against it — the reverse direction, in place.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| SCHEMBL13228941 | 0.86 | SMN1; SMN2 (0.56) | LMNAALDH1A1SMN1; SMN2RAB9ATP53 | |
| SCHEMBL19397824 | 0.84 | FGFR1 (0.56) | LMNAALDH1A1SMN1; SMN2RAB9ATP53 | |
| SCHEMBL4446092 | 0.84 | LMNA (0.60) | LMNAALDH1A1SMN1; SMN2RAB9ATP53 | |
| SCHEMBL28391493 | 0.82 | SMN1; SMN2 (0.60) | LMNAALDH1A1SMN1; SMN2RAB9ATP53 | |
| SCHEMBL505248 | 0.81 | LMNA (0.57) | LMNAALDH1A1SMN1; SMN2RAB9ATP53 | |
| SCHEMBL27516914 | 0.81 | ALDH1A1 (0.58) | LMNAALDH1A1SMN1; SMN2RAB9ATP53 | |
| SCHEMBL5166558 | 0.80 | SMN1; SMN2 (0.75) | LMNAALDH1A1SMN1; SMN2RAB9ATP53 | |
| SCHEMBL13228930 | 0.79 | HTT (0.62) | LMNAALDH1A1SMN1; SMN2RAB9ATSHR | |
| SCHEMBL8471993 | 0.78 | LMNA (0.58) | LMNAALDH1A1SMN1; SMN2RAB9ATP53 | |
| SCHEMBL29106646 | 0.78 | LMNA (0.58) | LMNAALDH1A1SMN1; SMN2RAB9ATP53 |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 1 patent. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| US-4339595-A | Hexa(meta-,para-carboxyphenyl)benzene compounds | STANDARD OIL COMPANY (INDIANA) (US) | 1982-07-13 | — | — | US | disclosed |