Predicted protein targets (top 20)
| gene | UniProt | supporting neighbours | confidence | |
|---|---|---|---|---|
| ▸ | MAPT | P10636 | 4/20 | 0.62 |
| ▸ | RAB9A | P51151 | 2/20 | 0.62 |
| ▸ | LPAR1 | Q92633 | 3/20 | 0.55 |
| ▸ | LPAR5 | Q9H1C0 | 3/20 | 0.55 |
| ▸ | NPC1 | O15118 | 1/20 | 0.54 |
| ▸ | SMN1; SMN2 | Q16637 | 1/20 | 0.54 |
| ▸ | L3MBTL1 | Q9Y468 | 2/20 | 0.51 |
| ▸ | TDP1 | Q9NUW8 | 1/20 | 0.51 |
| ▸ | HDAC1 | Q13547 | 2/20 | 0.49 |
| ▸ | HDAC6 | Q9UBN7 | 2/20 | 0.49 |
| ▸ | KDM4E | B2RXH2 | 1/20 | 0.49 |
| ▸ | SLC2A1 | P11166 | 1/20 | 0.48 |
| ▸ | CYP1A2 | P05177 | 1/20 | 0.48 |
| ▸ | CYP3A4 | P08684 | 1/20 | 0.48 |
| ▸ | CYP2D6 | P10635 | 1/20 | 0.48 |
| ▸ | CYP2C9 | P11712 | 1/20 | 0.48 |
| ▸ | ALOX12 | P18054 | 1/20 | 0.48 |
| ▸ | CYP2C19 | P33261 | 1/20 | 0.48 |
| ▸ | HTT | P42858 | 1/20 | 0.48 |
| ▸ | NPSR1 | Q6W5P4 | 1/20 | 0.48 |
Click a target to see other patent compounds predicted against it — the reverse direction, in place.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| SCHEMBL1122947 | 0.87 | LPAR1 (0.59) | LPAR1LPAR5 | |
| SCHEMBL1123361 | 0.86 | MAPT (0.67) | MAPTRAB9ANPC1SMN1; SMN2L3MBTL1 | |
| SCHEMBL6335583 | 0.82 | MAOB (0.60) | MAPTRAB9ANPC1SMN1; SMN2L3MBTL1 | |
| SCHEMBL8967341 | 0.81 | SLC2A1 (0.54) | NPC1HDAC1HDAC6SLC2A1CYP3A4 | |
| SCHEMBL20249538 | 0.81 | LTA4H (0.63) | MAPTRAB9ASMN1; SMN2 | |
| SCHEMBL4364300 | 0.80 | MAPT (0.74) | MAPTRAB9ANPC1SMN1; SMN2L3MBTL1 | |
| SCHEMBL1123270 | 0.80 | ALOX5 (0.53) | MAPTRAB9ALPAR1LPAR5NPC1 | |
| Hydrochloric Acid SCHEMBL8967290 | 0.80 | SLC2A1 (0.53) | NPC1HDAC1HDAC6SLC2A1CYP3A4 | |
| SCHEMBL9270086 | 0.79 | ACHE (0.54) | MAPTNPC1L3MBTL1CYP1A2CYP3A4 | |
| SCHEMBL16506845 | 0.79 | LPAR1 (0.83) | LPAR1LPAR5HDAC1HDAC6 |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 1 patent. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| EP-1644321-B1 | NEW BENZAMIDES AS PPATY MODULATORS | S A L V A T LAB SA (ES) | 2011-02-09 | — | — | EP | disclosed |