Predicted protein targets (top 7)
| gene | UniProt | supporting neighbours | confidence | |
|---|---|---|---|---|
| ▸ | LPAR1 | Q92633 | 17/20 | 0.59 |
| ▸ | LPAR5 | Q9H1C0 | 17/20 | 0.59 |
| ▸ | PKM | P14618 | 1/20 | 0.58 |
| ▸ | NR4A1 | P22736 | 1/20 | 0.55 |
| ▸ | NR4A2 | P43354 | 1/20 | 0.55 |
| ▸ | NR4A3 | Q92570 | 1/20 | 0.55 |
| ▸ | PLA2G4B | P0C869 | 1/20 | 0.53 |
Click a target to see other patent compounds predicted against it — the reverse direction, in place.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| SCHEMBL5936689 | 0.89 | GAA (0.52) | LPAR1LPAR5PKM | |
| SCHEMBL1122800 | 0.87 | MAPT (0.62) | LPAR1LPAR5 | |
| SCHEMBL8967341 | 0.85 | SLC2A1 (0.54) | — | |
| SCHEMBL1122672 | 0.84 | PKM (0.63) | LPAR1LPAR5PKMNR4A1NR4A2 | |
| SCHEMBL1123270 | 0.84 | ALOX5 (0.53) | LPAR1LPAR5NR4A1NR4A2NR4A3 | |
| Hydrochloric Acid SCHEMBL8967290 | 0.84 | SLC2A1 (0.53) | — | |
| SCHEMBL14569771 | 0.82 | TSHR (0.69) | PKMNR4A1NR4A2NR4A3 | |
| SCHEMBL6335583 | 0.81 | MAOB (0.60) | — | |
| SCHEMBL8359489 | 0.80 | KMT2A (0.69) | LPAR1LPAR5 | |
| SCHEMBL9080720 | 0.80 | TSHR (0.50) | LPAR1 |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 2 patents. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| EP-1644321-B1 | NEW BENZAMIDES AS PPATY MODULATORS | S A L V A T LAB SA (ES) | 2011-02-09 | — | — | EP | disclosed |
| US-20060160894-A1 | Benzamides as ppar modulators | LABORATORIOS S.A.L.V.A.T.,S.A. (ES) | 2006-07-20 | — | — | US | disclosed |
Patent text — is the patent's own abstract consistent with the prediction?
For each of this compound's patents that has machine-readable text (1 of them — usually the abstract, not the full specification), we ask MedCPT which protein the text reads most about, and where the chemistry-predicted target lands among 4885 human targets. A high rank means the patent's own wording is consistent with the prediction — a weak, independent signal, not proof of activity.
| Patent | Title | Text reads most about | Predicted target · text-rank |
|---|---|---|---|
| US-20060160894-A1 | Benzamides as ppar modulators | PPARD, PPARA, PPARG | LPAR1 608/4885LPAR5 698/4885PKM 1028/4885 |
“Text reads most about” is the patent abstract's nearest protein in MedCPT space (background-debiased). Only ~1.4% of patents have machine-readable text, so most compounds won't have this panel.