SCHEMBL11228215

SCHEMBL11228215

CCCCON=C(C(N)=O)c1ccccc1

nearest known ligand 0.49

Predicted protein targets (top 13)

geneUniProtsupporting neighboursconfidence
GAA P10253 1/20 0.49
CYP2C19 P33261 1/20 0.49
ESR1 P03372 1/20 0.45
CES2 O00748 3/20 0.44
CES1 P23141 3/20 0.44
PPARA Q07869 5/20 0.44
LMNA P02545 1/20 0.42
PPARG P37231 4/20 0.42
TDP1 Q9NUW8 2/20 0.41
L3MBTL1 Q9Y468 2/20 0.41
TSHR P16473 1/20 0.41
TBXA2R P21731 3/20 0.41
TBXAS1 P24557 3/20 0.41

Click a target to see other patent compounds predicted against it — the reverse direction, in place.

Similar compounds — the chemically nearest patent molecules

Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.

Compoundsimilaritytop predictedshared targets
SCHEMBL11236201 0.95 GAA (0.47) GAACYP2C19CES2CES1PPARA
SCHEMBL11241570 0.94 CES2 (0.48) GAACYP2C19CES2CES1PPARA
SCHEMBL11243831 0.91 CYP2C19 (0.51) GAACYP2C19CES2CES1PPARA
SCHEMBL22758100 0.91 CYP2C19 (0.51) GAACYP2C19CES2CES1PPARA
SCHEMBL11228210 0.85 ESR1 (0.45) ESR1CES2CES1PPARALMNA
SCHEMBL11228208 0.85 ESR1 (0.45) ESR1CES2CES1PPARALMNA
SCHEMBL8448454 0.84 GAA (0.55) GAACYP2C19CES2CES1LMNA
SCHEMBL22758101 0.84 GAA (0.55) GAACYP2C19CES2CES1LMNA
SCHEMBL8448451 0.84 GAA (0.55) GAACYP2C19CES2CES1LMNA
SCHEMBL11236194 0.81 CES2 (0.46) CES2CES1PPARALMNAPPARG

Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.

Patent provenance — the patents this molecule appears in, and who filed them

Claimed or disclosed in 8 patents. claimed = in the patent's claims; disclosed = body only.

PatentTitleAssigneePublishedPriorityFilingCountryStatus
CN-105399666-A Fungicide hydroxyimino-heterocyclic derivatives BAYER CROSPSCIENCE AG 2016-03-16 CN claimed
CN-102725270-B Fungicide hydroxyimino-heterocyclic derivatives BAYER CROPSCIENCE AG (DE) 2015-10-07 CN claimed
CN-102725270-A Fungicide hydroxyimino-heterocyclic derivatives BAYER CROPSCIENCE AG 2012-10-10 CN claimed
CN-105399666-A Fungicide hydroxyimino-heterocyclic derivatives BAYER CROSPSCIENCE AG 2016-03-16 CN disclosed
CN-102725270-B Fungicide hydroxyimino-heterocyclic derivatives BAYER CROPSCIENCE AG (DE) 2015-10-07 CN disclosed
CN-102725270-A Fungicide hydroxyimino-heterocyclic derivatives BAYER CROPSCIENCE AG 2012-10-10 CN disclosed
US-4342760-A ANTIMICROBIAL AGENTS FUJISAWA PHARMACEUTICAL COMPANY, LTD. (JP) 1982-08-03 US disclosed
US-4264597-A FUNGICIDES FUJISAWA PHARMACEUTICAL CO., LTD., NO. 3, 4-CHOME, DOSHOMACHI, HIGASHI-KU, OSAKA, JAPAN 1981-04-28 US disclosed