Predicted protein targets (top 20)
| gene | UniProt | supporting neighbours | confidence | |
|---|---|---|---|---|
| ▸ | GAA | P10253 | 1/20 | 0.47 |
| ▸ | CYP2C19 | P33261 | 1/20 | 0.47 |
| ▸ | CES2 | O00748 | 2/20 | 0.46 |
| ▸ | CES1 | P23141 | 2/20 | 0.46 |
| ▸ | PPARA | Q07869 | 3/20 | 0.46 |
| ▸ | LMNA | P02545 | 3/20 | 0.44 |
| ▸ | CYP3A4 | P08684 | 2/20 | 0.44 |
| ▸ | MEN1 | O00255 | 1/20 | 0.44 |
| ▸ | NR1I2 | O75469 | 1/20 | 0.44 |
| ▸ | CHRM2 | P08172 | 1/20 | 0.44 |
| ▸ | ADRA2A | P08913 | 1/20 | 0.44 |
| ▸ | MAPT | P10636 | 1/20 | 0.44 |
| ▸ | OPRK1 | P41145 | 1/20 | 0.44 |
| ▸ | HTR2B | P41595 | 1/20 | 0.44 |
| ▸ | SLC6A3 | Q01959 | 1/20 | 0.44 |
| ▸ | KMT2A | Q03164 | 1/20 | 0.44 |
| ▸ | HDAC6 | Q9UBN7 | 1/20 | 0.44 |
| ▸ | PPARG | P37231 | 2/20 | 0.44 |
| ▸ | TBXA2R | P21731 | 4/20 | 0.43 |
| ▸ | TSHR | P16473 | 2/20 | 0.43 |
Click a target to see other patent compounds predicted against it — the reverse direction, in place.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| SCHEMBL11241570 | 0.99 | CES2 (0.48) | GAACYP2C19CES2CES1PPARA | |
| SCHEMBL11228215 | 0.95 | GAA (0.49) | GAACYP2C19CES2CES1PPARA | |
| SCHEMBL22758100 | 0.89 | CYP2C19 (0.51) | GAACYP2C19CES2CES1PPARA | |
| SCHEMBL11243831 | 0.89 | CYP2C19 (0.51) | GAACYP2C19CES2CES1PPARA | |
| SCHEMBL11236197 | 0.85 | CES2 (0.46) | CES2CES1PPARALMNACYP3A4 | |
| SCHEMBL11236194 | 0.85 | CES2 (0.46) | CES2CES1PPARALMNACYP3A4 | |
| SCHEMBL11241569 | 0.84 | CES2 (0.48) | CES2CES1PPARALMNAPPARG | |
| SCHEMBL11241565 | 0.84 | CES2 (0.48) | CES2CES1PPARALMNAPPARG | |
| SCHEMBL8448451 | 0.83 | GAA (0.55) | GAACYP2C19CES2CES1LMNA | |
| SCHEMBL8448454 | 0.83 | GAA (0.55) | GAACYP2C19CES2CES1LMNA |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 2 patents. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| US-4342760-A | ANTIMICROBIAL AGENTS | FUJISAWA PHARMACEUTICAL COMPANY, LTD. (JP) | 1982-08-03 | — | — | US | disclosed |
| US-4264597-A | FUNGICIDES | FUJISAWA PHARMACEUTICAL CO., LTD., NO. 3, 4-CHOME, DOSHOMACHI, HIGASHI-KU, OSAKA, JAPAN | 1981-04-28 | — | — | US | disclosed |