SCHEMBL22758100

SCHEMBL22758100

CCCO/N=C(/C(N)=O)c1ccccc1

nearest known ligand 0.51

Predicted protein targets (top 20)

geneUniProtsupporting neighboursconfidence
CYP2C19 P33261 2/20 0.51
GAA P10253 1/20 0.51
LMNA P02545 3/20 0.49
PPARA Q07869 3/20 0.46
PPARG P37231 2/20 0.46
L3MBTL1 Q9Y468 4/20 0.40
TDP1 Q9NUW8 3/20 0.40
KMT2A Q03164 2/20 0.40
SMN1; SMN2 Q16637 1/20 0.39
NPSR1 Q6W5P4 1/20 0.39
MAPK1 P28482 1/20 0.39
HTT P42858 1/20 0.39
CES2 O00748 1/20 0.39
CES1 P23141 1/20 0.39
ALDH1A1 P00352 1/20 0.39
MEN1 O00255 1/20 0.38
POLB P06746 1/20 0.38
CYP3A4 P08684 1/20 0.38
PARP1 P09874 1/20 0.38
MAPT P10636 1/20 0.38

Click a target to see other patent compounds predicted against it — the reverse direction, in place.

Similar compounds — the chemically nearest patent molecules

Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.

Compoundsimilaritytop predictedshared targets
SCHEMBL11243831 1.00 CYP2C19 (0.51) CYP2C19GAALMNAPPARAPPARG
SCHEMBL11228215 0.91 GAA (0.49) CYP2C19GAALMNAPPARAPPARG
SCHEMBL11236201 0.89 GAA (0.47) CYP2C19GAALMNAPPARAPPARG
SCHEMBL11241570 0.88 CES2 (0.48) CYP2C19GAALMNAPPARAPPARG
SCHEMBL8448454 0.87 GAA (0.55) CYP2C19GAALMNAL3MBTL1TDP1
SCHEMBL8448451 0.87 GAA (0.55) CYP2C19GAALMNAL3MBTL1TDP1
SCHEMBL22758101 0.87 GAA (0.55) CYP2C19GAALMNAL3MBTL1TDP1
SCHEMBL6152765 0.87 LMNA (0.51) LMNAPPARAPPARGL3MBTL1KMT2A
SCHEMBL11243823 0.84 LMNA (0.49) LMNAPPARAPPARGL3MBTL1KMT2A
SCHEMBL11243827 0.84 LMNA (0.49) LMNAPPARAPPARGL3MBTL1KMT2A

Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.

Patent provenance — the patents this molecule appears in, and who filed them

Claimed or disclosed in 1 patent. claimed = in the patent's claims; disclosed = body only.

PatentTitleAssigneePublishedPriorityFilingCountryStatus
WO-2020244968-A1 FUNGICIDAL N-(PYRID-3-YL)CARBOXAMIDES BASF SE (DE) 2020-12-10 WO disclosed