Predicted protein targets (top 11)
| gene | UniProt | supporting neighbours | confidence | |
|---|---|---|---|---|
| ▸ | ESR1 | P03372 | 1/20 | 0.45 |
| ▸ | CES2 | O00748 | 3/20 | 0.44 |
| ▸ | CES1 | P23141 | 3/20 | 0.44 |
| ▸ | PPARA | Q07869 | 6/20 | 0.44 |
| ▸ | LMNA | P02545 | 1/20 | 0.42 |
| ▸ | PPARG | P37231 | 5/20 | 0.42 |
| ▸ | TSHR | P16473 | 1/20 | 0.41 |
| ▸ | TDP1 | Q9NUW8 | 1/20 | 0.41 |
| ▸ | L3MBTL1 | Q9Y468 | 1/20 | 0.41 |
| ▸ | TBXA2R | P21731 | 4/20 | 0.41 |
| ▸ | TBXAS1 | P24557 | 4/20 | 0.41 |
Click a target to see other patent compounds predicted against it — the reverse direction, in place.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| SCHEMBL11228210 | 1.00 | ESR1 (0.45) | ESR1CES2CES1PPARALMNA | |
| SCHEMBL11236197 | 0.95 | CES2 (0.46) | CES2CES1PPARALMNAPPARG | |
| SCHEMBL11236194 | 0.95 | CES2 (0.46) | CES2CES1PPARALMNAPPARG | |
| SCHEMBL11241565 | 0.94 | CES2 (0.48) | CES2CES1PPARALMNAPPARG | |
| SCHEMBL11241569 | 0.94 | CES2 (0.48) | CES2CES1PPARALMNAPPARG | |
| SCHEMBL11243827 | 0.91 | LMNA (0.49) | CES2CES1PPARALMNAPPARG | |
| SCHEMBL11243823 | 0.91 | LMNA (0.49) | CES2CES1PPARALMNAPPARG | |
| SCHEMBL11228215 | 0.85 | GAA (0.49) | ESR1CES2CES1PPARALMNA | |
| SCHEMBL11236782 | 0.84 | SMN1; SMN2 (0.44) | CES2CES1LMNATSHRTDP1 | |
| SCHEMBL11236778 | 0.84 | SMN1; SMN2 (0.44) | CES2CES1LMNATSHRTDP1 |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 2 patents. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| US-4342760-A | ANTIMICROBIAL AGENTS | FUJISAWA PHARMACEUTICAL COMPANY, LTD. (JP) | 1982-08-03 | — | — | US | disclosed |
| US-4264597-A | FUNGICIDES | FUJISAWA PHARMACEUTICAL CO., LTD., NO. 3, 4-CHOME, DOSHOMACHI, HIGASHI-KU, OSAKA, JAPAN | 1981-04-28 | — | — | US | disclosed |