Predicted protein targets (top 19)
| gene | UniProt | supporting neighbours | confidence | |
|---|---|---|---|---|
| ▸ | ERAP1 | Q9NZ08 | 4/20 | 0.55 |
| ▸ | ERAP2 | Q6P179 | 3/20 | 0.55 |
| ▸ | ANPEP | P15144 | 2/20 | 0.55 |
| ▸ | CTSC | P53634 | 2/20 | 0.51 |
| ▸ | HPGD | P15428 | 2/20 | 0.50 |
| ▸ | MEN1 | O00255 | 1/20 | 0.50 |
| ▸ | HTT | P42858 | 1/20 | 0.50 |
| ▸ | KMT2A | Q03164 | 1/20 | 0.50 |
| ▸ | SMN1; SMN2 | Q16637 | 1/20 | 0.50 |
| ▸ | LNPEP | Q9UIQ6 | 4/20 | 0.49 |
| ▸ | TSHR | P16473 | 1/20 | 0.49 |
| ▸ | CPA1 | P15085 | 4/20 | 0.48 |
| ▸ | CPA2 | P48052 | 4/20 | 0.48 |
| ▸ | CPA4 | Q9UI42 | 4/20 | 0.48 |
| ▸ | ACP3 | P15309 | 1/20 | 0.47 |
| ▸ | CTSB | P07858 | 1/20 | 0.46 |
| ▸ | CTSH | P09668 | 1/20 | 0.46 |
| ▸ | CTSS | P25774 | 1/20 | 0.46 |
| ▸ | CTSK | P43235 | 1/20 | 0.46 |
Click a target to see other patent compounds predicted against it — the reverse direction, in place.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| SCHEMBL1582573 | 0.86 | CTSC (0.56) | ERAP2ANPEPCTSC | |
| SCHEMBL23013070 | 0.81 | ACE (0.61) | ERAP2ANPEPCTSCMEN1KMT2A | |
| SCHEMBL23013068 | 0.81 | ACE (0.61) | ERAP2ANPEPCTSCMEN1KMT2A | |
| SCHEMBL1582649 | 0.81 | OPRD1 (0.52) | ANPEPCTSC | |
| SCHEMBL23030452 | 0.78 | LNPEP (0.64) | ERAP1ERAP2CTSCSMN1; SMN2LNPEP | |
| SCHEMBL28574389 | 0.78 | LNPEP (0.64) | ERAP1ERAP2CTSCSMN1; SMN2LNPEP | |
| SCHEMBL2567389 | 0.77 | TSHR (0.54) | ERAP1ERAP2ANPEPCTSCHPGD | |
| SCHEMBL2567392 | 0.77 | TSHR (0.54) | ERAP1ERAP2ANPEPCTSCHPGD | |
| SCHEMBL6247713 | 0.77 | TSHR (0.54) | ERAP1ERAP2ANPEPCTSCHPGD | |
| SCHEMBL17706116 | 0.77 | LTA4H (0.61) | ERAP1ERAP2ANPEPLNPEP |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 2 patents. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| JP-57098294-A | — | — | None | — | — | JP | disclosed |
| JP-S5798294-A | PHOSPHONODIPEPTIDES | GRELAN PHARMACEUT CO LTD | 1982-06-18 | — | — | JP | disclosed |