Predicted protein targets (top 9)
| gene | UniProt | supporting neighbours | confidence | |
|---|---|---|---|---|
| ▸ | LNPEP | Q9UIQ6 | 12/20 | 0.64 |
| ▸ | MAPT | P10636 | 1/20 | 0.55 |
| ▸ | L3MBTL1 | Q9Y468 | 1/20 | 0.55 |
| ▸ | CTSC | P53634 | 1/20 | 0.51 |
| ▸ | ERAP2 | Q6P179 | 5/20 | 0.51 |
| ▸ | TSHR | P16473 | 1/20 | 0.49 |
| ▸ | ERAP1 | Q9NZ08 | 5/20 | 0.48 |
| ▸ | ACE | P12821 | 1/20 | 0.48 |
| ▸ | SMN1; SMN2 | Q16637 | 1/20 | 0.48 |
Click a target to see other patent compounds predicted against it — the reverse direction, in place.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| SCHEMBL23030452 | 1.00 | LNPEP (0.64) | LNPEPMAPTL3MBTL1CTSCERAP2 | |
| SCHEMBL28574400 | 0.89 | LNPEP (0.55) | LNPEPCTSCERAP2TSHRERAP1 | |
| SCHEMBL28574398 | 0.89 | LNPEP (0.55) | LNPEPCTSCERAP2TSHRERAP1 | |
| SCHEMBL23013070 | 0.87 | ACE (0.61) | LNPEPCTSCERAP2TSHRACE | |
| SCHEMBL23013068 | 0.87 | ACE (0.61) | LNPEPCTSCERAP2TSHRACE | |
| SCHEMBL8231968 | 0.86 | LNPEP (0.56) | LNPEPCTSCERAP2TSHRERAP1 | |
| SCHEMBL345990 | 0.86 | LNPEP (0.56) | LNPEPCTSCERAP2TSHRERAP1 | |
| SCHEMBL13135022 | 0.86 | MAPT (0.57) | MAPTL3MBTL1CTSC | |
| SCHEMBL17452277 | 0.84 | OPRK1 (0.52) | LNPEPCTSCERAP2ERAP1 | |
| SCHEMBL276649 | 0.84 | LTA4H (0.53) | LNPEPCTSCERAP2TSHRERAP1 |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 4 patents. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| CN-117964684-A | MASP-2 inhibitors and methods of use | 奥默罗斯公司 | 2024-05-03 | — | — | CN | disclosed |
| CN-117964683-A | MASP-2 inhibitors and methods of use | 奥默罗斯公司 | 2024-05-03 | — | — | CN | disclosed |
| CN-114269431-A | Enzyme inhibitors | 卡尔维斯塔制药有限公司 | 2022-04-01 | — | — | CN | disclosed |
| CN-112867706-A | MASP-2 inhibitors and methods of use | 奥默罗斯公司 | 2021-05-28 | — | — | CN | disclosed |