Predicted protein targets (top 20)
| gene | UniProt | supporting neighbours | confidence | |
|---|---|---|---|---|
| ▸ | EPHX1 | P07099 | 6/20 | 0.45 |
| ▸ | NPC1 | O15118 | 4/20 | 0.45 |
| ▸ | SMN1; SMN2 | Q16637 | 4/20 | 0.45 |
| ▸ | RAB9A | P51151 | 3/20 | 0.45 |
| ▸ | MAPT | P10636 | 2/20 | 0.45 |
| ▸ | KDM4E | B2RXH2 | 1/20 | 0.45 |
| ▸ | ALDH1A1 | P00352 | 1/20 | 0.45 |
| ▸ | CYP3A4 | P08684 | 1/20 | 0.45 |
| ▸ | EPHX2 | P34913 | 1/20 | 0.45 |
| ▸ | HTT | P42858 | 1/20 | 0.42 |
| ▸ | ADRA2A | P08913 | 1/20 | 0.41 |
| ▸ | PDE4A | P27815 | 1/20 | 0.41 |
| ▸ | ADRA1A | P35348 | 1/20 | 0.41 |
| ▸ | PKM | P14618 | 1/20 | 0.41 |
| ▸ | SRD5A2 | P31213 | 1/20 | 0.39 |
| ▸ | MEN1 | O00255 | 1/20 | 0.39 |
| ▸ | LMNA | P02545 | 1/20 | 0.39 |
| ▸ | KMT2A | Q03164 | 1/20 | 0.39 |
| ▸ | MMP2 | P08253 | 3/20 | 0.39 |
| ▸ | CA12 | O43570 | 2/20 | 0.39 |
Click a target to see other patent compounds predicted against it — the reverse direction, in place.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| SCHEMBL6684532 | 0.81 | EPHX1 (0.48) | EPHX1NPC1SMN1; SMN2RAB9AMAPT | |
| SCHEMBL27460412 | 0.79 | EPHX1 (0.45) | EPHX1NPC1SMN1; SMN2RAB9AMAPT | |
| SCHEMBL3073114 | 0.77 | EPHX1 (0.44) | EPHX1NPC1SMN1; SMN2RAB9AMAPT | |
| SCHEMBL30151503 | 0.76 | ALDH1A1 (0.46) | EPHX1NPC1SMN1; SMN2RAB9AMAPT | |
| SCHEMBL31174196 | 0.76 | EPHX1 (0.42) | EPHX1NPC1SMN1; SMN2RAB9AMAPT | |
| SCHEMBL9547549 | 0.75 | EPHX1 (0.54) | EPHX1NPC1SMN1; SMN2RAB9AMAPT | |
| SCHEMBL29087524 | 0.73 | ADRA2A (0.41) | EPHX1NPC1SMN1; SMN2RAB9AMAPT | |
| SCHEMBL3083216 | 0.73 | CES2 (0.41) | EPHX1SMN1; SMN2ALDH1A1 | |
| SCHEMBL11377433 | 0.72 | ADRA2A (0.40) | EPHX1NPC1SMN1; SMN2RAB9AMAPT | |
| SCHEMBL9538240 | 0.72 | EPHX1 (0.50) | EPHX1NPC1SMN1; SMN2RAB9AMAPT |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 1 patent. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| US-4318924-A | Combating bacteria with N-cycloalkyl-N'-substituted-N'-acyl-ureas | BAYER AKTIENGESELLSCHAFT (DE) | 1982-03-09 | — | — | US | claimed |