Predicted protein targets (top 8)
| gene | UniProt | supporting neighbours | confidence | |
|---|---|---|---|---|
| ▸ | GPR132 | Q9UNW8 | 16/20 | 0.57 |
| ▸ | CMKLR2 | P46091 | 1/20 | 0.50 |
| ▸ | CMKLR1 | Q99788 | 1/20 | 0.50 |
| ▸ | PTPN1 | P18031 | 2/20 | 0.48 |
| ▸ | PTPN2 | P17706 | 1/20 | 0.43 |
| ▸ | CDC25B | P30305 | 1/20 | 0.43 |
| ▸ | ITGB3 | P05106 | 1/20 | 0.43 |
| ▸ | ITGA2B | P08514 | 1/20 | 0.43 |
Click a target to see other patent compounds predicted against it — the reverse direction, in place.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| SCHEMBL1122913 | 0.90 | PTPN1 (0.56) | GPR132PTPN1PTPN2CDC25BITGB3 | |
| SCHEMBL1123431 | 0.85 | GPR132 (0.61) | GPR132CMKLR2CMKLR1PTPN1ITGB3 | |
| SCHEMBL1123228 | 0.84 | GPR132 (0.60) | GPR132CMKLR2CMKLR1PTPN1ITGB3 | |
| SCHEMBL1123192 | 0.84 | GPR132 (0.63) | GPR132CMKLR2CMKLR1PTPN1ITGB3 | |
| SCHEMBL1123368 | 0.82 | GPR132 (0.60) | GPR132CMKLR2CMKLR1PTPN1ITGB3 | |
| SCHEMBL1122844 | 0.80 | MEN1 (0.63) | GPR132CMKLR2CMKLR1 | |
| SCHEMBL1122981 | 0.80 | ITGB2 (0.52) | GPR132 | |
| SCHEMBL1123282 | 0.77 | PTPN1 (0.58) | GPR132CMKLR2CMKLR1PTPN1PTPN2 | |
| SCHEMBL1123050 | 0.77 | PTPN1 (0.69) | GPR132PTPN1ITGB3ITGA2B | |
| SCHEMBL5720732 | 0.75 | NR4A2 (0.62) | — |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 1 patent. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| EP-1644321-B1 | NEW BENZAMIDES AS PPATY MODULATORS | S A L V A T LAB SA (ES) | 2011-02-09 | — | — | EP | disclosed |