Predicted protein targets (top 13)
| gene | UniProt | supporting neighbours | confidence | |
|---|---|---|---|---|
| ▸ | LPAR1 | Q92633 | 4/20 | 0.45 |
| ▸ | SLC2A1 | P11166 | 1/20 | 0.45 |
| ▸ | F10 | P00742 | 2/20 | 0.44 |
| ▸ | MEP1B | Q16820 | 1/20 | 0.43 |
| ▸ | HDAC1 | Q13547 | 1/20 | 0.43 |
| ▸ | HDAC6 | Q9UBN7 | 1/20 | 0.43 |
| ▸ | PPARG | P37231 | 2/20 | 0.43 |
| ▸ | PPARA | Q07869 | 1/20 | 0.43 |
| ▸ | NR1H3 | Q13133 | 1/20 | 0.43 |
| ▸ | KMT2A | Q03164 | 1/20 | 0.43 |
| ▸ | LPAR5 | Q9H1C0 | 1/20 | 0.42 |
| ▸ | F2 | P00734 | 1/20 | 0.42 |
| ▸ | F7 | P08709 | 1/20 | 0.42 |
Click a target to see other patent compounds predicted against it — the reverse direction, in place.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| SCHEMBL1122385 | 0.93 | PPARG (0.47) | LPAR1SLC2A1F10MEP1BHDAC1 | |
| SCHEMBL1123465 | 0.91 | SLC2A1 (0.51) | LPAR1SLC2A1F10MEP1BHDAC1 | |
| SCHEMBL1123244 | 0.90 | LPAR1 (0.52) | LPAR1SLC2A1F10MEP1BPPARG | |
| SCHEMBL1122983 | 0.89 | NR4A1 (0.46) | LPAR1SLC2A1F10MEP1BHDAC1 | |
| SCHEMBL1123395 | 0.84 | F10 (0.51) | LPAR1F10MEP1BHDAC1HDAC6 | |
| SCHEMBL1122959 | 0.84 | LPAR1 (0.54) | LPAR1SLC2A1HDAC1HDAC6LPAR5 | |
| SCHEMBL1122692 | 0.83 | LPAR1 (0.55) | LPAR1SLC2A1HDAC1HDAC6PPARG | |
| SCHEMBL1122912 | 0.83 | LPAR1 (0.49) | LPAR1SLC2A1F10MEP1BPPARG | |
| SCHEMBL1123557 | 0.83 | PTGES (0.52) | SLC2A1F10PPARGKMT2A | |
| SCHEMBL1123247 | 0.83 | SLC2A1 (0.47) | LPAR1SLC2A1F10MEP1BHDAC1 |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 1 patent. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| EP-1644321-B1 | NEW BENZAMIDES AS PPATY MODULATORS | S A L V A T LAB SA (ES) | 2011-02-09 | — | — | EP | disclosed |