Predicted protein targets (top 20)
| gene | UniProt | supporting neighbours | confidence | |
|---|---|---|---|---|
| ▸ | PPARG | P37231 | 2/20 | 0.47 |
| ▸ | F10 | P00742 | 2/20 | 0.46 |
| ▸ | CA12 | O43570 | 1/20 | 0.45 |
| ▸ | CA1 | P00915 | 1/20 | 0.45 |
| ▸ | CA2 | P00918 | 1/20 | 0.45 |
| ▸ | CA4 | P22748 | 1/20 | 0.45 |
| ▸ | PPARA | Q07869 | 1/20 | 0.45 |
| ▸ | HDAC1 | Q13547 | 3/20 | 0.43 |
| ▸ | HDAC3 | O15379 | 1/20 | 0.43 |
| ▸ | HDAC2 | Q92769 | 1/20 | 0.43 |
| ▸ | HDAC8 | Q9BY41 | 1/20 | 0.43 |
| ▸ | LPAR1 | Q92633 | 2/20 | 0.43 |
| ▸ | SLC2A1 | P11166 | 1/20 | 0.43 |
| ▸ | KMT2A | Q03164 | 1/20 | 0.42 |
| ▸ | F2 | P00734 | 1/20 | 0.42 |
| ▸ | F7 | P08709 | 1/20 | 0.42 |
| ▸ | ACHE | P22303 | 2/20 | 0.41 |
| ▸ | KDM4E | B2RXH2 | 1/20 | 0.41 |
| ▸ | MEP1B | Q16820 | 1/20 | 0.41 |
| ▸ | HDAC6 | Q9UBN7 | 2/20 | 0.41 |
Click a target to see other patent compounds predicted against it — the reverse direction, in place.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| SCHEMBL1122881 | 0.93 | LPAR1 (0.45) | PPARGF10PPARAHDAC1LPAR1 | |
| SCHEMBL1123395 | 0.90 | F10 (0.51) | PPARGF10HDAC1HDAC3HDAC2 | |
| SCHEMBL1123247 | 0.89 | SLC2A1 (0.47) | PPARGF10HDAC1HDAC3HDAC8 | |
| SCHEMBL1122912 | 0.89 | LPAR1 (0.49) | PPARGF10PPARALPAR1SLC2A1 | |
| SCHEMBL1123557 | 0.89 | PTGES (0.52) | PPARGF10SLC2A1KMT2ABCHE | |
| SCHEMBL1123394 | 0.88 | KMT2A (0.52) | PPARGF10PPARAKMT2A | |
| SCHEMBL1123593 | 0.87 | NR4A1 (0.48) | PPARGF10CA12CA1CA2 | |
| SCHEMBL1123465 | 0.84 | SLC2A1 (0.51) | PPARGF10HDAC1LPAR1SLC2A1 | |
| SCHEMBL1122949 | 0.83 | FFAR1 (0.52) | PPARGPPARASLC2A1BCHE | |
| SCHEMBL1123244 | 0.83 | LPAR1 (0.52) | PPARGF10PPARALPAR1SLC2A1 |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 1 patent. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| EP-1644321-B1 | NEW BENZAMIDES AS PPATY MODULATORS | S A L V A T LAB SA (ES) | 2011-02-09 | — | — | EP | disclosed |