Predicted protein targets (top 6)
| gene | UniProt | supporting neighbours | confidence | |
|---|---|---|---|---|
| ▸ | LPAR1 | Q92633 | 11/20 | 0.54 |
| ▸ | LPAR5 | Q9H1C0 | 10/20 | 0.54 |
| ▸ | LTA4H | P09960 | 2/20 | 0.50 |
| ▸ | HDAC1 | Q13547 | 1/20 | 0.48 |
| ▸ | HDAC6 | Q9UBN7 | 1/20 | 0.48 |
| ▸ | SLC2A1 | P11166 | 1/20 | 0.46 |
Click a target to see other patent compounds predicted against it — the reverse direction, in place.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| SCHEMBL1122692 | 0.95 | LPAR1 (0.55) | LPAR1LPAR5LTA4HHDAC1HDAC6 | |
| SCHEMBL1122952 | 0.92 | LPAR1 (0.53) | LPAR1LPAR5LTA4HHDAC1HDAC6 | |
| SCHEMBL1123244 | 0.88 | LPAR1 (0.52) | LPAR1LPAR5SLC2A1 | |
| SCHEMBL1123335 | 0.88 | LPAR1 (0.52) | LPAR1LPAR5LTA4HSLC2A1 | |
| SCHEMBL1123465 | 0.84 | SLC2A1 (0.51) | LPAR1LPAR5LTA4HHDAC1HDAC6 | |
| SCHEMBL1122881 | 0.84 | LPAR1 (0.45) | LPAR1LPAR5HDAC1HDAC6SLC2A1 | |
| SCHEMBL1122983 | 0.82 | NR4A1 (0.46) | LPAR1HDAC1HDAC6SLC2A1 | |
| SCHEMBL1122949 | 0.81 | FFAR1 (0.52) | SLC2A1 | |
| SCHEMBL1122912 | 0.81 | LPAR1 (0.49) | LPAR1LPAR5SLC2A1 | |
| SCHEMBL1122837 | 0.80 | PPARG (0.51) | LPAR1LPAR5SLC2A1 |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 1 patent. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| EP-1644321-B1 | NEW BENZAMIDES AS PPATY MODULATORS | S A L V A T LAB SA (ES) | 2011-02-09 | — | — | EP | disclosed |