Predicted protein targets (top 20)
| gene | UniProt | supporting neighbours | confidence | |
|---|---|---|---|---|
| ▸ | TXNRD1 | Q16881 | 1/20 | 0.58 |
| ▸ | TXNRD3 | Q86VQ6 | 1/20 | 0.58 |
| ▸ | TXNRD2 | Q9NNW7 | 1/20 | 0.58 |
| ▸ | MAPT | P10636 | 4/20 | 0.56 |
| ▸ | ALDH1A1 | P00352 | 4/20 | 0.56 |
| ▸ | GAA | P10253 | 1/20 | 0.51 |
| ▸ | NPSR1 | Q6W5P4 | 1/20 | 0.51 |
| ▸ | MGLL | Q99685 | 4/20 | 0.48 |
| ▸ | CYP1A2 | P05177 | 1/20 | 0.48 |
| ▸ | SMN1; SMN2 | Q16637 | 2/20 | 0.47 |
| ▸ | GPR35 | Q9HC97 | 2/20 | 0.47 |
| ▸ | TP53 | P04637 | 1/20 | 0.47 |
| ▸ | HPGD | P15428 | 1/20 | 0.47 |
| ▸ | TSHR | P16473 | 1/20 | 0.47 |
| ▸ | MAPK1 | P28482 | 1/20 | 0.47 |
| ▸ | FAAH | O00519 | 3/20 | 0.46 |
| ▸ | MEN1 | O00255 | 1/20 | 0.45 |
| ▸ | HTT | P42858 | 1/20 | 0.45 |
| ▸ | KMT2A | Q03164 | 1/20 | 0.45 |
| ▸ | TDP1 | Q9NUW8 | 1/20 | 0.45 |
Click a target to see other patent compounds predicted against it — the reverse direction, in place.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| SCHEMBL11097893 | 0.76 | TDP1 (0.48) | MAPTALDH1A1GAATSHRMAPK1 | |
| SCHEMBL41110 | 0.75 | TXNRD1 (0.72) | TXNRD1TXNRD3TXNRD2MAPTALDH1A1 | |
| SCHEMBL41109 | 0.75 | TXNRD1 (0.72) | TXNRD1TXNRD3TXNRD2MAPTALDH1A1 | |
| SCHEMBL13783415 | 0.75 | TXNRD1 (0.62) | TXNRD1TXNRD3TXNRD2MAPTALDH1A1 | |
| SCHEMBL30128616 | 0.75 | TXNRD1 (0.78) | TXNRD1TXNRD3TXNRD2MAPTALDH1A1 | |
| SCHEMBL6161726 | 0.75 | TXNRD1 (0.78) | TXNRD1TXNRD3TXNRD2MAPTALDH1A1 | |
| SCHEMBL1032814 | 0.75 | TXNRD1 (1.00) | TXNRD1TXNRD3TXNRD2MAPTALDH1A1 | |
| SCHEMBL8964242 | 0.74 | MAPT (0.61) | TXNRD1TXNRD3TXNRD2MAPTALDH1A1 | |
| SCHEMBL8963352 | 0.74 | MAPT (0.61) | TXNRD1TXNRD3TXNRD2MAPTALDH1A1 | |
| SCHEMBL396790 | 0.74 | MAPT (0.74) | TXNRD1TXNRD3TXNRD2MAPTALDH1A1 |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 2 patents. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| US-4328311-A | USEFUL IN IMMUNOASSAY | SYVA COMPANY (US) | 1982-05-04 | — | — | US | disclosed |
| US-4220722-A | ACYLATION, AMIDATION, SULFIDING | SYVA COMPANY (US) | 1980-09-02 | — | — | US | disclosed |