Predicted protein targets (top 15)
| gene | UniProt | supporting neighbours | confidence | |
|---|---|---|---|---|
| ▸ | TDP1 | Q9NUW8 | 1/20 | 0.48 |
| ▸ | CES1 | P23141 | 2/20 | 0.46 |
| ▸ | MEN1 | O00255 | 2/20 | 0.45 |
| ▸ | MAPT | P10636 | 2/20 | 0.45 |
| ▸ | KMT2A | Q03164 | 2/20 | 0.45 |
| ▸ | CES2 | O00748 | 1/20 | 0.44 |
| ▸ | SRD5A2 | P31213 | 1/20 | 0.44 |
| ▸ | CA1 | P00915 | 2/20 | 0.44 |
| ▸ | CA2 | P00918 | 2/20 | 0.44 |
| ▸ | TRPA1 | O75762 | 2/20 | 0.44 |
| ▸ | GAA | P10253 | 1/20 | 0.44 |
| ▸ | ALDH1A1 | P00352 | 3/20 | 0.43 |
| ▸ | TSHR | P16473 | 1/20 | 0.43 |
| ▸ | MAPK1 | P28482 | 1/20 | 0.43 |
| ▸ | LMNA | P02545 | 1/20 | 0.42 |
Click a target to see other patent compounds predicted against it — the reverse direction, in place.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| SCHEMBL8754771 | 0.82 | CYP2C9 (0.50) | MEN1MAPTKMT2AALDH1A1MAPK1 | |
| SCHEMBL7353270 | 0.78 | ALDH1A1 (0.49) | CES1MEN1MAPTKMT2ATRPA1 | |
| SCHEMBL874253 | 0.77 | HTT (0.62) | TDP1MEN1MAPTKMT2ATRPA1 | |
| SCHEMBL3393493 | 0.77 | TRPA1 (0.45) | TDP1CES1MEN1MAPTKMT2A | |
| SCHEMBL5491118 | 0.77 | TDP1 (0.43) | TDP1CES1MEN1MAPTKMT2A | |
| Cadaverine Tartrate SCHEMBL28015424 | 0.77 | TDP1 (0.59) | TDP1CES1MEN1MAPTKMT2A | |
| SCHEMBL11228942 | 0.76 | TXNRD1 (0.58) | TDP1MEN1MAPTKMT2ACES2 | |
| SCHEMBL7924853 | 0.75 | MEN1 (0.44) | TDP1CES1MEN1MAPTKMT2A | |
| SCHEMBL6421123 | 0.75 | MAPK1 (0.52) | TDP1CES1MEN1MAPTKMT2A | |
| SCHEMBL74368 | 0.74 | LMNA (0.44) | TDP1MAPTGAAALDH1A1TSHR |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 1 patent. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| US-4461911-A | FROM THIOGLYCOLIC ACID AND AN ARYLDIAZONIUM SALT, COPPER SALT, ACID MEDIUM | BAYER AKTIENGESELLSCHAFT (DE) | 1984-07-24 | — | — | US | disclosed |