Predicted protein targets (top 20)
| gene | UniProt | supporting neighbours | confidence | |
|---|---|---|---|---|
| ▸ | TXNRD1 | Q16881 | 1/20 | 0.72 |
| ▸ | TXNRD3 | Q86VQ6 | 1/20 | 0.72 |
| ▸ | TXNRD2 | Q9NNW7 | 1/20 | 0.72 |
| ▸ | MAPT | P10636 | 6/20 | 0.61 |
| ▸ | GAA | P10253 | 1/20 | 0.61 |
| ▸ | NPSR1 | Q6W5P4 | 1/20 | 0.61 |
| ▸ | ALDH1A1 | P00352 | 4/20 | 0.58 |
| ▸ | GPR35 | Q9HC97 | 2/20 | 0.58 |
| ▸ | SMN1; SMN2 | Q16637 | 2/20 | 0.58 |
| ▸ | TP53 | P04637 | 1/20 | 0.58 |
| ▸ | HPGD | P15428 | 1/20 | 0.58 |
| ▸ | TSHR | P16473 | 1/20 | 0.58 |
| ▸ | MAPK1 | P28482 | 1/20 | 0.58 |
| ▸ | TDP1 | Q9NUW8 | 1/20 | 0.55 |
| ▸ | MGLL | Q99685 | 6/20 | 0.54 |
| ▸ | FAAH | O00519 | 5/20 | 0.54 |
| ▸ | HIF1A | Q16665 | 1/20 | 0.53 |
| ▸ | HTT | P42858 | 2/20 | 0.52 |
| ▸ | MEN1 | O00255 | 1/20 | 0.52 |
| ▸ | KMT2A | Q03164 | 1/20 | 0.52 |
Click a target to see other patent compounds predicted against it — the reverse direction, in place.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| SCHEMBL41109 | 1.00 | TXNRD1 (0.72) | TXNRD1TXNRD3TXNRD2MAPTGAA | |
| SCHEMBL6161726 | 0.84 | TXNRD1 (0.78) | TXNRD1TXNRD3TXNRD2MAPTGAA | |
| SCHEMBL1032814 | 0.84 | TXNRD1 (1.00) | TXNRD1TXNRD3TXNRD2MAPTGAA | |
| SCHEMBL30128616 | 0.84 | TXNRD1 (0.78) | TXNRD1TXNRD3TXNRD2MAPTGAA | |
| SCHEMBL3990991 | 0.82 | TXNRD1 (0.75) | TXNRD1TXNRD3TXNRD2MAPTGAA | |
| SCHEMBL13783415 | 0.81 | TXNRD1 (0.62) | TXNRD1TXNRD3TXNRD2MAPTGAA | |
| SCHEMBL8973665 | 0.81 | TXNRD1 (0.72) | TXNRD1TXNRD3TXNRD2MAPTGAA | |
| SCHEMBL434275 | 0.81 | TXNRD1 (0.72) | TXNRD1TXNRD3TXNRD2MAPTGAA | |
| SCHEMBL11686247 | 0.81 | TXNRD1 (0.72) | TXNRD1TXNRD3TXNRD2MAPTGAA | |
| SCHEMBL8442596 | 0.81 | TXNRD1 (0.72) | TXNRD1TXNRD3TXNRD2MAPTGAA |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 940 patents — showing the first 20. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| EP-3606528-B1 | TRICYCLIC COMPOUNDS AS GLYCOGEN SYNTHASE KINASE 3 (GSK3) INHIBITORS AND USES THEREOF | BROAD INST INC (US) | 2023-10-18 | — | — | EP | claimed |
| EP-3649135-B1 | SYNTHESIS OF HALICHONDRINS | HARVARD COLLEGE (US) | 2022-12-28 | — | — | EP | claimed |
| EP-3172213-B1 | MACROCYCLIC KINASE INHIBITORS AND USES THEREOF | DANA FARBER CANCER INST INC (US) | 2021-09-22 | — | — | EP | claimed |
| EP-3092220-B1 | VITAMIN C PRODRUGS AND USES THEREOF | UNIV FLORIDA (US) | 2021-01-20 | — | — | EP | claimed |
| EP-3171874-B1 | IMIDAZOLYL KINASE INHIBITORS AND USES THEREOF | DANA FARBER CANCER INST INC (US) | 2020-11-18 | — | — | EP | claimed |
| EP-2016044-B1 | PENTACYCLINE DERIVATIVES FOR THE TREATMENT OF INFECTIONS | HARVARD COLLEGE (US) | 2020-06-10 | — | — | EP | claimed |
| EP-3063164-B1 | SYNTHETIC ROUTE TO 2'-DEOXY-2',2'-DIFLUOROTETRAHYDROURIDINES | OTSUKA PHARMA CO LTD (JP) | 2018-12-05 | — | — | EP | claimed |
| EP-2727915-B1 | Synthesis of deuterated catechols and benzo[d][1,3]dioxoles and derivatives thereof | CONCERT PHARMACEUTICALS INC (US) | 2016-04-13 | — | — | EP | claimed |
| US-20100048957-A1 | METHOD TO PREPARE PURE CURCUMIN | KIM DARRICK S H L | 2010-02-25 | — | — | US | claimed |
| EP-2037762-A4 | METHOD TO PREPARE PURE CURCUMIN | KIM DARRICK S H L (US) | 2009-07-08 | — | — | EP | claimed |
| EP-2037762-A1 | METHOD TO PREPARE PURE CURCUMIN | Kim, Darrick S.H.L. (US) | 2009-03-25 | — | — | EP | claimed |
| WO-2007143635-A1 | METHOD TO PREPARE PURE CURCUMIN | KIM DARRICK S (US) | 2007-12-13 | — | — | WO | claimed |
| US-5478928-A | Useful as antiviral agents in the treatment and prevention of AIDS | SOUTHERN RESEARCH INSTITUTE (US) | 1995-12-26 | — | — | US | claimed |
| WO-1995011685-A1 | 2',3'-DIDEOXY-4'-THIORIBONUCLEOSIDES AS ANTIVIRAL AGENTS | SOUTHERN RESEARCH INSTITUTE (US) | 1995-05-04 | — | — | WO | claimed |
| US-12551570-B2 | Compounds comprising cleavable linker and uses thereof | INTOCELL, INC. (KR) | 2026-02-17 | — | — | US | disclosed |
| US-12479927-B2 | Compounds comprising cleavable linker and uses thereof | INTOCELL, INC. (KR) | 2025-11-25 | — | — | US | disclosed |
| US-20250213712-A1 | ANTIBODY DRUG CONJUGATES COMPRISING CAMPTOTHECIN DERIVATIVES AND USES THEREOF | INTOCELL, INC. (KR) | 2025-07-03 | — | — | US | disclosed |
| US-4876338-A | Synthesis of azetidinones using CuCl | SCHERING CORPORATION (US) | 1989-10-24 | — | — | US | disclosed |
| US-4767853-A | Synthesis of 1-(allyloxycarbonyl)-methyl-3-(hydroxyethyl)-4-beta-naphthoxythiocarbonylthio-2-azetidinones and hydroxy protected analogs thereof | SCHERING CORPORATION (US) | 1988-08-30 | — | — | US | disclosed |
| EP-0257610-A2 | Process and intermediates for the synthesis of the enantiomers of bicyclo(4.2.0)oct-2-en-7-one and derivatives and for the synthesis of bicyclo(4.2.0)octane derivatives | SYNTEX (U.S.A.) INC. (US) | 1988-03-02 | — | — | EP | disclosed |
Patent text — is the patent's own abstract consistent with the prediction?
For each of this compound's patents that has machine-readable text (3 of them — usually the abstract, not the full specification), we ask MedCPT which protein the text reads most about, and where the chemistry-predicted target lands among 4885 human targets. A high rank means the patent's own wording is consistent with the prediction — a weak, independent signal, not proof of activity.
| Patent | Title | Text reads most about | Predicted target · text-rank |
|---|---|---|---|
| US-20250213712-A1 | ANTIBODY DRUG CONJUGATES COMPRISING CAMPTOTHECIN DERIVATIVES AND USES THEREOF | CD47, TOP2A, SSB | TXNRD1 579/4885TXNRD3 657/4885TXNRD2 1035/4885 |
| US-12551570-B2 | Compounds comprising cleavable linker and uses thereof | FCGR2A, FCGR3B, FCGR1A | TXNRD1 2745/4885TXNRD3 3787/4885TXNRD2 3943/4885 |
| US-12479927-B2 | Compounds comprising cleavable linker and uses thereof | VIP, ANTXR2, TNFRSF9 | TXNRD1 1177/4885TXNRD3 1643/4885TXNRD2 1490/4885 |
“Text reads most about” is the patent abstract's nearest protein in MedCPT space (background-debiased). Only ~1.4% of patents have machine-readable text, so most compounds won't have this panel.