Predicted protein targets (top 20)
| gene | UniProt | supporting neighbours | confidence | |
|---|---|---|---|---|
| ▸ | CASP3 | P42574 | 3/20 | 0.49 |
| ▸ | GSK3B | P49841 | 1/20 | 0.47 |
| ▸ | ELANE | P08246 | 2/20 | 0.43 |
| ▸ | KDM4E | B2RXH2 | 2/20 | 0.43 |
| ▸ | ALDH1A1 | P00352 | 2/20 | 0.43 |
| ▸ | CYP1A2 | P05177 | 1/20 | 0.43 |
| ▸ | CYP3A4 | P08684 | 1/20 | 0.43 |
| ▸ | CYP2D6 | P10635 | 1/20 | 0.43 |
| ▸ | CYP2C9 | P11712 | 1/20 | 0.43 |
| ▸ | CYP2C19 | P33261 | 1/20 | 0.43 |
| ▸ | MEN1 | O00255 | 1/20 | 0.43 |
| ▸ | POLB | P06746 | 1/20 | 0.43 |
| ▸ | KMT2A | Q03164 | 1/20 | 0.43 |
| ▸ | CTSG | P08311 | 1/20 | 0.42 |
| ▸ | CASP2 | P42575 | 1/20 | 0.41 |
| ▸ | CASP7 | P55210 | 1/20 | 0.41 |
| ▸ | CASP6 | P55212 | 1/20 | 0.41 |
| ▸ | CASP8 | Q14790 | 1/20 | 0.41 |
| ▸ | DAO | P14920 | 1/20 | 0.41 |
| ▸ | GAA | P10253 | 1/20 | 0.41 |
Click a target to see other patent compounds predicted against it — the reverse direction, in place.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| SCHEMBL30554084 | 0.91 | CASP3 (0.43) | CASP3GSK3BELANEKDM4EALDH1A1 | |
| SCHEMBL10685681 | 0.90 | CASP3 (0.43) | CASP3GSK3BKDM4EALDH1A1MEN1 | |
| SCHEMBL29805947 | 0.90 | CASP3 (0.43) | CASP3GSK3BKDM4EALDH1A1MEN1 | |
| SCHEMBL28371583 | 0.89 | CASP3 (0.44) | CASP3GSK3BELANEKDM4EALDH1A1 | |
| SCHEMBL10713059 | 0.87 | GSK3B (0.50) | CASP3GSK3BKDM4EALDH1A1CYP1A2 | |
| SCHEMBL8498986 | 0.87 | MAOA (0.50) | CASP3GSK3BGAAMAOAMAOB | |
| Tetraethylene Glycol SCHEMBL28997246 | 0.86 | UPP1 (0.45) | CASP3GSK3BELANEKDM4EALDH1A1 | |
| SCHEMBL30184679 | 0.85 | ALDH1A1 (0.41) | CASP3GSK3BKDM4EALDH1A1MEN1 | |
| SCHEMBL28486594 | 0.85 | KCNQ2 (0.40) | CASP3GSK3BKDM4EALDH1A1CYP1A2 | |
| SCHEMBL28320631 | 0.85 | DAO (0.41) | CASP3ELANEALDH1A1CYP1A2CYP3A4 |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 75 patents — showing the first 20. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| CN-115872877-A | Synthesis method of aminotetraethyleneglycol | 南京安伦化工科技有限公司 | 2023-03-31 | — | — | CN | claimed |
| CN-109305968-B | A kind of preparation method of stable isotope labeling 6-benzyladenine internal standard reagent | 坛墨质检科技股份有限公司 | 2019-09-27 | — | — | CN | claimed |
| CN-109305968-A | A kind of preparation method of stable isotope labeling 6-benzyladenine internal standard reagent | 坛墨质检科技股份有限公司 | 2019-02-05 | — | — | CN | claimed |
| CN-109293554-A | It is the method that one step of starting material constructs N- benzylphthalimide using imines | 桂林理工大学 | 2019-02-01 | — | — | CN | claimed |
| CN-101379031-B | Improved process for preparing stable nitroxyl radicals | POLIMERI EUROPA SPA | 2012-03-28 | — | — | CN | claimed |
| US-8034362-B2 | Chemical composition of hydrogels for use as articulating surfaces | ZIMMER, INC. (US) | 2011-10-11 | — | — | US | claimed |
| US-7982052-B2 | Process for the preparation of stable nitroxyl radicals | POLIMERI EUROPA S.P.A. (IT) | 2011-07-19 | — | — | US | claimed |
| EP-2237807-A2 | HYDROGEL COMPOSITIONS AND USES THEREOF | Zimmer, Inc. (US) | 2010-10-13 | — | — | EP | claimed |
| US-20100240909-A1 | PROCESS FOR THE PREPARATION OF STABLE NITROXYL RADICALS | POLIMERI EUROPA S.P.A. (IT) | 2010-09-23 | — | — | US | claimed |
| EP-1984335-B1 | IMPROVED PROCESS FOR THE PREPARATION OF STABLE NITROXYL RADICALS | POLIMERI EUROPA SPA (IT) | 2009-08-19 | — | — | EP | claimed |
| US-20090175919-A1 | CHEMICAL COMPOSITION OF HYDROGELS FOR USE AS ARTICULATING SURFACES | ZIMMER, INC. (US) | 2009-07-09 | — | — | US | claimed |
| CN-101379031-A | Improved process for preparing stable nitroxyl radicals | POLIMERI EUROPA SPA (IT) | 2009-03-04 | — | — | CN | claimed |
| EP-1984335-A1 | IMPROVED PROCESS FOR THE PREPARATION OF STABLE NITROXYL RADICALS | Polimeri Europa S.p.A. (IT) | 2008-10-29 | — | — | EP | claimed |
| WO-2007093452-A1 | IMPROVED PROCESS FOR THE PREPARATION OF STABLE NITROXYL RADICALS | POLIMERI EUROPA S.P.A. (IT) | 2007-08-23 | — | — | WO | claimed |
| EP-1789387-A1 | PERFECTED PROCESS FOR THE PREPARATION OF STABLE NITROXIDE RADICALS | Polimeri Europa S.p.A. (IT) | 2007-05-30 | — | — | EP | claimed |
| WO-2006029697-A1 | PERFECTED PROCESS FOR THE PREPARATION OF STABLE NITROXIDE RADICALS | POLIMERI EUROPA S.P.A. (IT) | 2006-03-23 | — | — | WO | claimed |
| EP-1601651-A1 | PROCESS FOR THE PREPARATION OF 1,1,3,3-TETRAALKYLISOINDOLINES STARTING FROM N-BENZYLPHTHALIMIDE | Polimeri Europa S.p.A. (IT) | 2005-12-07 | — | — | EP | claimed |
| EP-1503754-A1 | BETA-AGONIST COMPOUNDS COMPRISING NITRIC OXIDE DONOR GROUPS AND REACTIVE OXYGEN SPECIES SCAVENGER GROUPS AND THEIR USE IN THE TREATMENT OF RESPIRATORY DISORDERS | Yissum Research Development Company, of The Hebrew University of Jerusalem (IL) | 2005-02-09 | — | — | EP | claimed |
| WO-2004078720-A1 | PROCESS FOR THE PREPARATION OF 1,1,3,3-TETRAALKYLISOINDOLINE STARTING FROM N-BENZYLPHTHALIMIDE | POLIMERI EUROPA S.P.A. (IT) | 2004-09-16 | — | — | WO | claimed |
| WO-2003088961-A1 | BETA-AGONIST COMPOUNDS COMPRISING NITRIC OXIDE DONOR GROUPS AND REACTIVE OXYGEN SPECIES SCAVENGER GROUPS AND THEIR USE IN THE TREATMENT OF RESPIRATORY DISORDERS | YISSUM RESEARCH DEVELOPMENT COMPANY OF THE HEBREW UNIVERSITY OF JERUSALEM (IL) | 2003-10-30 | — | — | WO | claimed |
Patent text — is the patent's own abstract consistent with the prediction?
For each of this compound's patents that has machine-readable text (1 of them — usually the abstract, not the full specification), we ask MedCPT which protein the text reads most about, and where the chemistry-predicted target lands among 4885 human targets. A high rank means the patent's own wording is consistent with the prediction — a weak, independent signal, not proof of activity.
| Patent | Title | Text reads most about | Predicted target · text-rank |
|---|---|---|---|
| US-20100240909-A1 | PROCESS FOR THE PREPARATION OF STABLE NITROXYL RADICALS | PPOX, TET1, PBRM1 | CASP3 585/4885GSK3B 2806/4885ELANE 3304/4885 |
“Text reads most about” is the patent abstract's nearest protein in MedCPT space (background-debiased). Only ~1.4% of patents have machine-readable text, so most compounds won't have this panel.