Predicted protein targets (top 20)
| gene | UniProt | supporting neighbours | confidence | |
|---|---|---|---|---|
| ▸ | JUN | P05412 | 1/20 | 0.63 |
| ▸ | EGFR | P00533 | 3/20 | 0.61 |
| ▸ | MAPT | P10636 | 5/20 | 0.61 |
| ▸ | VCP | P55072 | 3/20 | 0.61 |
| ▸ | SMN1; SMN2 | Q16637 | 2/20 | 0.61 |
| ▸ | ALDH1A1 | P00352 | 2/20 | 0.61 |
| ▸ | LMNA | P02545 | 2/20 | 0.61 |
| ▸ | HTT | P42858 | 2/20 | 0.61 |
| ▸ | GALR2 | O43603 | 1/20 | 0.61 |
| ▸ | MAPK1 | P28482 | 1/20 | 0.61 |
| ▸ | SYK | P43405 | 1/20 | 0.61 |
| ▸ | NPSR1 | Q6W5P4 | 1/20 | 0.61 |
| ▸ | POLB | P06746 | 3/20 | 0.60 |
| ▸ | TDP1 | Q9NUW8 | 1/20 | 0.60 |
| ▸ | GFER | P55789 | 1/20 | 0.58 |
| ▸ | MEN1 | O00255 | 3/20 | 0.58 |
| ▸ | KMT2A | Q03164 | 3/20 | 0.58 |
| ▸ | GAA | P10253 | 3/20 | 0.54 |
| ▸ | PIM1 | P11309 | 1/20 | 0.53 |
| ▸ | TUBB4A | P04350 | 1/20 | 0.51 |
Click a target to see other patent compounds predicted against it — the reverse direction, in place.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| SCHEMBL11229392 | 0.89 | VCP (0.69) | JUNEGFRMAPTVCPSMN1; SMN2 | |
| SCHEMBL3198139 | 0.84 | JUN (0.81) | JUNEGFRMAPTSMN1; SMN2LMNA | |
| SCHEMBL3198145 | 0.84 | JUN (0.81) | JUNEGFRMAPTSMN1; SMN2LMNA | |
| SCHEMBL4499495 | 0.84 | JUN (0.62) | JUNEGFRMAPTSMN1; SMN2ALDH1A1 | |
| SCHEMBL4499494 | 0.84 | JUN (0.62) | JUNEGFRMAPTSMN1; SMN2ALDH1A1 | |
| SCHEMBL344482 | 0.83 | EGFR (0.66) | JUNEGFRMAPTSMN1; SMN2ALDH1A1 | |
| SCHEMBL374530 | 0.83 | EGFR (0.66) | JUNEGFRMAPTSMN1; SMN2ALDH1A1 | |
| SCHEMBL29672623 | 0.83 | EGFR (0.66) | JUNEGFRMAPTSMN1; SMN2ALDH1A1 | |
| SCHEMBL17693076 | 0.83 | JUN (0.71) | JUNEGFRMAPTSMN1; SMN2ALDH1A1 | |
| SCHEMBL6035433 | 0.83 | JUN (0.75) | JUNEGFRMAPTSMN1; SMN2ALDH1A1 |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 3 patents. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| US-4318986-A | Enzyme assays | NATIONAL RESEARCH DEVELOPMENT CORPORATION (GB) | 1982-03-09 | — | — | US | disclosed |
| EP-0007372-A1 | Methods and reagents for the assay of enzymes | NATIONAL RESEARCH DEVELOPMENT CORPORATION (GB) | 1980-02-06 | — | — | EP | disclosed |
| WO-1979000255-A1 | ENZYME ASSAYS | NAT RES DEV (GB) | 1979-05-17 | — | — | WO | disclosed |