Predicted protein targets (top 20)
| gene | UniProt | supporting neighbours | confidence | |
|---|---|---|---|---|
| ▸ | EGFR | P00533 | 2/20 | 0.66 |
| ▸ | XDH | P47989 | 1/20 | 0.63 |
| ▸ | MAPT | P10636 | 5/20 | 0.61 |
| ▸ | SMN1; SMN2 | Q16637 | 1/20 | 0.61 |
| ▸ | POLB | P06746 | 4/20 | 0.60 |
| ▸ | TDP1 | Q9NUW8 | 2/20 | 0.60 |
| ▸ | JUN | P05412 | 1/20 | 0.60 |
| ▸ | GFER | P55789 | 1/20 | 0.59 |
| ▸ | MEN1 | O00255 | 4/20 | 0.55 |
| ▸ | KMT2A | Q03164 | 4/20 | 0.55 |
| ▸ | ERN1 | O75460 | 1/20 | 0.55 |
| ▸ | SIRT1 | Q96EB6 | 1/20 | 0.53 |
| ▸ | ALDH1A1 | P00352 | 3/20 | 0.53 |
| ▸ | KDM4E | B2RXH2 | 1/20 | 0.53 |
| ▸ | CYP3A4 | P08684 | 1/20 | 0.53 |
| ▸ | ALOX15 | P16050 | 1/20 | 0.53 |
| ▸ | PRKDC | P78527 | 1/20 | 0.53 |
| ▸ | HSD17B10 | Q99714 | 1/20 | 0.53 |
| ▸ | GAA | P10253 | 3/20 | 0.51 |
| ▸ | PIM1 | P11309 | 1/20 | 0.50 |
Click a target to see other patent compounds predicted against it — the reverse direction, in place.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| SCHEMBL344482 | 1.00 | EGFR (0.66) | EGFRXDHMAPTSMN1; SMN2POLB | |
| SCHEMBL29672623 | 1.00 | EGFR (0.66) | EGFRXDHMAPTSMN1; SMN2POLB | |
| Methyl Alcohol SCHEMBL29087051 | 0.98 | EGFR (0.64) | EGFRXDHMAPTSMN1; SMN2POLB | |
| Cyclohexylamine SCHEMBL7798524 | 0.86 | POLB (0.56) | EGFRXDHMAPTSMN1; SMN2POLB | |
| SCHEMBL4499495 | 0.85 | JUN (0.62) | EGFRXDHMAPTSMN1; SMN2POLB | |
| SCHEMBL4499494 | 0.85 | JUN (0.62) | EGFRXDHMAPTSMN1; SMN2POLB | |
| SCHEMBL31337893 | 0.83 | TUBB4A (0.61) | EGFRXDHMAPTSMN1; SMN2POLB | |
| SCHEMBL1447403 | 0.83 | TUBB4A (0.61) | EGFRXDHMAPTSMN1; SMN2POLB | |
| SCHEMBL1515869 | 0.83 | XDH (0.58) | EGFRXDHMAPTSMN1; SMN2POLB | |
| SCHEMBL346053 | 0.83 | KMT2A (0.64) | EGFRXDHMAPTSMN1; SMN2POLB |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 1 patent. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| EP-2408789-A1 | DIASTEREOISOMERS OF HYPOPHOSPHOROUS ACID DERIVATIVES | Centre National De La Recherche Scientifique CNRS (FR) | 2012-01-25 | — | — | EP | disclosed |