Predicted protein targets (top 20)
| gene | UniProt | supporting neighbours | confidence | |
|---|---|---|---|---|
| ▸ | NR1H3 | Q13133 | 2/20 | 0.49 |
| ▸ | NR1H2 | P55055 | 1/20 | 0.49 |
| ▸ | KMT2A | Q03164 | 2/20 | 0.49 |
| ▸ | KDM4E | B2RXH2 | 1/20 | 0.49 |
| ▸ | EGFR | P00533 | 1/20 | 0.46 |
| ▸ | ERBB2 | P04626 | 1/20 | 0.46 |
| ▸ | HTT | P42858 | 3/20 | 0.46 |
| ▸ | OXTR | P30559 | 1/20 | 0.44 |
| ▸ | TARBP2 | Q15633 | 1/20 | 0.43 |
| ▸ | PDE10A | Q9Y233 | 1/20 | 0.43 |
| ▸ | SIRT2 | Q8IXJ6 | 1/20 | 0.42 |
| ▸ | MAOA | P21397 | 2/20 | 0.42 |
| ▸ | TSHR | P16473 | 1/20 | 0.41 |
| ▸ | HSD17B1 | P14061 | 1/20 | 0.41 |
| ▸ | HSD17B2 | P37059 | 1/20 | 0.41 |
| ▸ | ATM | Q13315 | 1/20 | 0.40 |
| ▸ | NPSR1 | Q6W5P4 | 2/20 | 0.40 |
| ▸ | ALDH1A1 | P00352 | 1/20 | 0.40 |
| ▸ | CYP3A4 | P08684 | 1/20 | 0.40 |
| ▸ | CYP2C9 | P11712 | 1/20 | 0.40 |
Click a target to see other patent compounds predicted against it — the reverse direction, in place.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| SCHEMBL11230427 | 0.88 | GFER (0.43) | NR1H3NR1H2KMT2AKDM4EHTT | |
| SCHEMBL11222632 | 0.86 | HIF1A (0.44) | NR1H3NR1H2KMT2AKDM4EEGFR | |
| SCHEMBL11232727 | 0.86 | HSD17B1 (0.54) | KMT2AKDM4EHTTHSD17B1HSD17B2 | |
| SCHEMBL11233109 | 0.85 | HSD17B2 (0.48) | MAOAHSD17B1HSD17B2KDM1AMAOB | |
| SCHEMBL11233224 | 0.84 | MLYCD (0.55) | KMT2AKDM4EHTTSIRT2TSHR | |
| SCHEMBL11222631 | 0.82 | PGR (0.44) | KMT2AHSD17B1HSD17B2NPSR1ALDH1A1 | |
| SCHEMBL11232766 | 0.82 | HTT (0.60) | KMT2AKDM4EEGFRERBB2HTT | |
| SCHEMBL11235143 | 0.81 | KMT2A (0.43) | KMT2AHTTNPSR1ALDH1A1CYP3A4 | |
| SCHEMBL9001651 | 0.80 | KMT2A (0.69) | NR1H3NR1H2KMT2AKDM4EEGFR | |
| SCHEMBL11251117 | 0.80 | SENP1 (0.48) | KDM4ETSHRHSD17B2NPSR1ALDH1A1 |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 2 patents. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| US-4361579-A | TREATMENT OF IMMUNE DISEASES WITH ORGANOGERMANIUM POLYMERS | YOSHITOMI PHARMACEUTICAL INDUSTRIES, LTD. (JP) | 1982-11-30 | — | — | US | disclosed |
| EP-0025965-A2 | Organogermanium compounds, a method for producing them and pharmaceutical compositions comprising them | Yoshitomi Pharmaceutical Industries, Ltd. (JP) | 1981-04-01 | — | — | EP | disclosed |