Predicted protein targets (top 18)
| gene | UniProt | supporting neighbours | confidence | |
|---|---|---|---|---|
| ▸ | CYP2C9 | P11712 | 3/20 | 0.51 |
| ▸ | CYP2C19 | P33261 | 3/20 | 0.51 |
| ▸ | TSHR | P16473 | 3/20 | 0.51 |
| ▸ | CYP3A4 | P08684 | 2/20 | 0.51 |
| ▸ | MEN1 | O00255 | 6/20 | 0.50 |
| ▸ | KMT2A | Q03164 | 6/20 | 0.50 |
| ▸ | ALDH1A1 | P00352 | 7/20 | 0.49 |
| ▸ | CYP1A2 | P05177 | 2/20 | 0.49 |
| ▸ | LMNA | P02545 | 2/20 | 0.49 |
| ▸ | GAA | P10253 | 2/20 | 0.47 |
| ▸ | SMN1; SMN2 | Q16637 | 4/20 | 0.46 |
| ▸ | MAPT | P10636 | 2/20 | 0.45 |
| ▸ | HPGD | P15428 | 1/20 | 0.45 |
| ▸ | NPSR1 | Q6W5P4 | 1/20 | 0.45 |
| ▸ | MAPK1 | P28482 | 3/20 | 0.44 |
| ▸ | USP2 | O75604 | 1/20 | 0.44 |
| ▸ | HTR6 | P50406 | 1/20 | 0.44 |
| ▸ | RCE1 | Q9Y256 | 1/20 | 0.43 |
Click a target to see other patent compounds predicted against it — the reverse direction, in place.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| SCHEMBL11229501 | 0.77 | RCE1 (0.64) | CYP2C9CYP2C19MEN1KMT2AALDH1A1 | |
| SCHEMBL17479807 | 0.73 | ALDH1A1 (0.60) | CYP2C9CYP2C19TSHRCYP3A4MEN1 | |
| SCHEMBL121325 | 0.69 | TOP2A (0.65) | MEN1KMT2AALDH1A1GAASMN1; SMN2 | |
| SCHEMBL31684035 | 0.69 | L3MBTL1 (0.74) | TSHRMEN1KMT2AALDH1A1GAA | |
| SCHEMBL28868160 | 0.69 | TOP2A (0.47) | CYP2C9CYP2C19MEN1KMT2AALDH1A1 | |
| SCHEMBL28853377 | 0.69 | SMN1; SMN2 (0.50) | TSHRMEN1KMT2AALDH1A1SMN1; SMN2 | |
| SCHEMBL19205947 | 0.69 | MAPT (0.61) | CYP2C9CYP2C19TSHRCYP3A4MEN1 | |
| SCHEMBL20435689 | 0.68 | CA9 (0.59) | CYP2C9CYP2C19TSHRCYP3A4MEN1 | |
| SCHEMBL1063351 | 0.68 | KMT2A (1.00) | CYP2C9CYP2C19TSHRCYP3A4MEN1 | |
| SCHEMBL5422444 | 0.67 | L3MBTL1 (0.76) | TSHRMEN1KMT2AALDH1A1GAA |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 1 patent. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| CN-107001283-B | FLT3 receptor antagonists | 国家健康与医学研究院 | 2021-05-25 | — | — | CN | disclosed |