Predicted protein targets (top 20)
| gene | UniProt | supporting neighbours | confidence | |
|---|---|---|---|---|
| ▸ | DRD3 | P35462 | 2/20 | 0.33 |
| ▸ | DRD2 | P14416 | 1/20 | 0.33 |
| ▸ | DRD4 | P21917 | 1/20 | 0.33 |
| ▸ | DPP4 | P27487 | 1/20 | 0.33 |
| ▸ | SLC6A4 | P31645 | 3/20 | 0.32 |
| ▸ | MAPK1 | P28482 | 1/20 | 0.32 |
| ▸ | PTPN7 | P35236 | 1/20 | 0.32 |
| ▸ | DUSP3 | P51452 | 1/20 | 0.32 |
| ▸ | PTPN5 | P54829 | 1/20 | 0.32 |
| ▸ | PTPN11 | Q06124 | 1/20 | 0.32 |
| ▸ | TAAR1 | Q96RJ0 | 1/20 | 0.32 |
| ▸ | CASR | P41180 | 2/20 | 0.32 |
| ▸ | STK17B | O94768 | 1/20 | 0.32 |
| ▸ | STK17A | Q9UEE5 | 1/20 | 0.32 |
| ▸ | HSP90AA1 | P07900 | 1/20 | 0.32 |
| ▸ | HSP90AB1 | P08238 | 1/20 | 0.32 |
| ▸ | NPC1 | O15118 | 1/20 | 0.32 |
| ▸ | RAB9A | P51151 | 1/20 | 0.32 |
| ▸ | HTR1A | P08908 | 1/20 | 0.31 |
| ▸ | ADRA2B | P18089 | 1/20 | 0.31 |
Click a target to see other patent compounds predicted against it — the reverse direction, in place.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| Hydrochloric Acid SCHEMBL11235609 | 0.99 | DRD3 (0.33) | DRD3DRD2DRD4DPP4SLC6A4 | |
| SCHEMBL11242830 | 0.90 | TRPV4 (0.35) | DRD2DRD4SLC6A4HSP90AA1HSP90AB1 | |
| SCHEMBL11231203 | 0.87 | NPC1 (0.38) | DRD3DRD2DRD4CASRHSP90AA1 | |
| Hydrochloric Acid SCHEMBL11226921 | 0.86 | RAB9A (0.37) | DRD3DRD2DRD4CASRHSP90AA1 | |
| SCHEMBL11244735 | 0.84 | TSHR (0.36) | DRD3DRD2DRD4SLC6A4MAPK1 | |
| SCHEMBL11229508 | 0.84 | THRB (0.42) | TAAR1HTR1AHTR2AALDH1A1MAPT | |
| Hydrochloric Acid SCHEMBL11238437 | 0.83 | THRB (0.41) | TAAR1HTR1AHTR2AALDH1A1MAPT | |
| Hydrochloric Acid SCHEMBL11237752 | 0.83 | TSHR (0.36) | DRD3DRD2DRD4SLC6A4MAPK1 | |
| SCHEMBL11237796 | 0.82 | GAA (0.43) | DRD3DRD2DRD4SLC6A4CASR | |
| SCHEMBL11238357 | 0.81 | NPC1 (0.43) | SLC6A4NPC1RAB9AALDH1A1MAPT |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 1 patent. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| US-4356322-A | ADRENERGIC STIMULANTS; CARDIOTONIC AGENTS | VEB ARZNEIMITTELWERK DRESDEN (DD) | 1982-10-26 | — | — | US | claimed |