SCHEMBL1122949

SCHEMBL1122949

O=C(O)CCN(Cc1cccc(OCc2ccccc2)c1)C(=O)c1ccc(OCCN(Cc2ccccc2)Cc2ccccc2)cc1

nearest known ligand 0.52

Predicted protein targets (top 10)

geneUniProtsupporting neighboursconfidence
FFAR1 O14842 2/20 0.52
PTGES O14684 2/20 0.52
SLC2A1 P11166 5/20 0.50
SLC2A4 P14672 1/20 0.50
BCHE P06276 5/20 0.49
ALOX5 P09917 2/20 0.48
LTC4S Q16873 1/20 0.48
PPARG P37231 1/20 0.47
PPARA Q07869 1/20 0.47
MAOB P27338 1/20 0.45

Click a target to see other patent compounds predicted against it — the reverse direction, in place.

Similar compounds — the chemically nearest patent molecules

Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.

Compoundsimilaritytop predictedshared targets
SCHEMBL1123557 0.94 PTGES (0.52) FFAR1PTGESSLC2A1SLC2A4BCHE
SCHEMBL1123394 0.93 KMT2A (0.52) FFAR1PTGESPPARGPPARAMAOB
SCHEMBL1122854 0.92 FFAR1 (0.60) FFAR1PTGESSLC2A1SLC2A4ALOX5
SCHEMBL1123335 0.91 LPAR1 (0.52) FFAR1PTGESSLC2A1ALOX5PPARG
SCHEMBL1123113 0.91 FFAR1 (0.62) FFAR1PTGESSLC2A1SLC2A4ALOX5
SCHEMBL1122963 0.90 FFAR1 (0.65) FFAR1PTGESSLC2A1SLC2A4ALOX5
SCHEMBL1123260 0.86 FFAR1 (0.60) FFAR1PTGESSLC2A1SLC2A4ALOX5
SCHEMBL1122952 0.86 LPAR1 (0.53) FFAR1
SCHEMBL1122912 0.86 LPAR1 (0.49) FFAR1PTGESSLC2A1ALOX5PPARG
SCHEMBL1123559 0.85 FFAR1 (0.62) FFAR1PTGESSLC2A1SLC2A4PPARG

Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.

Patent provenance — the patents this molecule appears in, and who filed them

Claimed or disclosed in 7 patents. claimed = in the patent's claims; disclosed = body only.

PatentTitleAssigneePublishedPriorityFilingCountryStatus
EP-1644321-B1 NEW BENZAMIDES AS PPATY MODULATORS S A L V A T LAB SA (ES) 2011-02-09 EP claimed
US-20060160894-A1 Benzamides as ppar modulators LABORATORIOS S.A.L.V.A.T.,S.A. (ES) 2006-07-20 US claimed
EP-1644321-B1 NEW BENZAMIDES AS PPATY MODULATORS S A L V A T LAB SA (ES) 2011-02-09 EP disclosed
CN-1835914-A New benzamides as PPAR[upsilon] modulators S A L V A T LAB SA (ES) 2006-09-20 CN disclosed
US-20060160894-A1 Benzamides as ppar modulators LABORATORIOS S.A.L.V.A.T.,S.A. (ES) 2006-07-20 US disclosed
EP-1644321-A2 NEW BENZAMIDES AS PPATY MODULATORS LABORATORIOS S.A.L.V.A.T., S.A. (ES) 2006-04-12 EP disclosed
WO-2004110983-A2 NEW BENZAMIDES AS PPARϒ MODULATORS LABORATORIOS S.A.L.V.A.T., S.A. (ES) 2004-12-23 WO disclosed

Patent text — is the patent's own abstract consistent with the prediction?

For each of this compound's patents that has machine-readable text (1 of them — usually the abstract, not the full specification), we ask MedCPT which protein the text reads most about, and where the chemistry-predicted target lands among 4885 human targets. A high rank means the patent's own wording is consistent with the prediction — a weak, independent signal, not proof of activity.

PatentTitleText reads most aboutPredicted target · text-rank
US-20060160894-A1 Benzamides as ppar modulators PPARD, PPARA, PPARG FFAR1 32/4885PTGES 110/4885SLC2A1 2494/4885

“Text reads most about” is the patent abstract's nearest protein in MedCPT space (background-debiased). Only ~1.4% of patents have machine-readable text, so most compounds won't have this panel.