⚠ Novel chemotype — no close known analogue (best Tanimoto < 0.3). Unexplored chemical space relative to ChEMBL.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| SCHEMBL4670206 | 0.76 | PKM (0.39) | — | |
| SCHEMBL4681145 | 0.73 | HTT (0.41) | — | |
| SCHEMBL11229667 | 0.73 | LMNA (0.41) | — | |
| SCHEMBL2991774 | 0.71 | HTT (0.43) | — | |
| SCHEMBL4681766 | 0.71 | HTT (0.43) | — | |
| SCHEMBL4684804 | 0.70 | CHRM2 (0.34) | — | |
| SCHEMBL23849709 | 0.70 | SLC6A2 (0.33) | — | |
| SCHEMBL23849717 | 0.70 | SLC6A2 (0.33) | — | |
| SCHEMBL14585063 | 0.70 | PIK3CD (0.34) | — | |
| SCHEMBL418973 | 0.70 | PIK3CD (0.34) | — |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 3 patents. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| EP-0040494-B1 | CARBAPENAMS AND CARBAPEN-2-EMS AND PROCESS THEREFOR | PFIZER INC. (US) | 1984-02-15 | — | — | EP | disclosed |
| US-4429128-A | CARBAPENICILLINS, THIENAMYCINS, BACTERICIDES | PFIZER INC. (US) | 1984-01-31 | — | — | US | disclosed |
| US-4348264-A | Photocatalyzed process for producing carbapenams and carbapen-2-ems | PFIZER INC. (US) | 1982-09-07 | — | — | US | disclosed |