Predicted protein targets (top 20)
| gene | UniProt | supporting neighbours | confidence | |
|---|---|---|---|---|
| ▸ | HTR6 | P50406 | 1/20 | 0.41 |
| ▸ | SMN1; SMN2 | Q16637 | 4/20 | 0.34 |
| ▸ | LMNA | P02545 | 3/20 | 0.34 |
| ▸ | HTT | P42858 | 3/20 | 0.34 |
| ▸ | GAA | P10253 | 2/20 | 0.34 |
| ▸ | KDM4E | B2RXH2 | 1/20 | 0.34 |
| ▸ | MAPT | P10636 | 1/20 | 0.34 |
| ▸ | ALOX15 | P16050 | 1/20 | 0.34 |
| ▸ | HDAC3 | O15379 | 1/20 | 0.33 |
| ▸ | HDAC1 | Q13547 | 1/20 | 0.33 |
| ▸ | HDAC7 | Q8WUI4 | 1/20 | 0.33 |
| ▸ | HDAC2 | Q92769 | 1/20 | 0.33 |
| ▸ | HDAC8 | Q9BY41 | 1/20 | 0.33 |
| ▸ | HDAC6 | Q9UBN7 | 1/20 | 0.33 |
| ▸ | HDAC9 | Q9UKV0 | 1/20 | 0.33 |
| ▸ | HDAC5 | Q9UQL6 | 1/20 | 0.33 |
| ▸ | KMT2A | Q03164 | 3/20 | 0.32 |
| ▸ | POLB | P06746 | 1/20 | 0.32 |
| ▸ | L3MBTL1 | Q9Y468 | 1/20 | 0.32 |
| ▸ | NPC1 | O15118 | 1/20 | 0.32 |
Click a target to see other patent compounds predicted against it — the reverse direction, in place.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| SCHEMBL11224804 | 0.88 | HTR6 (0.41) | HTR6SMN1; SMN2LMNAHTTGAA | |
| Hydrochloric Acid SCHEMBL11220602 | 0.87 | HTR6 (0.40) | HTR6SMN1; SMN2LMNAHTTGAA | |
| SCHEMBL11220623 | 0.81 | CYP19A1 (0.49) | HTR6SMN1; SMN2KDM4EMAPTHDAC3 | |
| SCHEMBL11235389 | 0.78 | HTR6 (0.66) | HTR6HDAC3HDAC1HDAC7HDAC2 | |
| SCHEMBL6439357 | 0.77 | HTR6 (0.32) | HTR6 | |
| Hydrochloric Acid SCHEMBL11233156 | 0.76 | HTR6 (0.64) | HTR6SMN1; SMN2KDM4EHDAC3HDAC1 | |
| SCHEMBL11238731 | 0.76 | HTR6 (0.41) | HTR6SMN1; SMN2LMNAHTTMAPT | |
| SCHEMBL9144106 | 0.75 | HTR1A (0.33) | HTR6 | |
| SCHEMBL8770362 | 0.74 | TRPA1 (0.30) | HTR6 | |
| SCHEMBL9145501 | 0.72 | — | — |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 1 patent. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| US-4357337-A | PIPERIDINYLALKYL DERIVATIVES | PHARMINDUSTRIE (FR) | 1982-11-02 | — | — | US | disclosed |