SCHEMBL8770362

SCHEMBL8770362

Cc1ccc2c(c1)C(C[SiH3])C=C2

nearest known ligand 0.30

Predicted protein targets (top 4)

geneUniProtsupporting neighboursconfidence
TRPA1 O75762 1/20 0.30
HTR6 P50406 1/20 0.30
CHRNB2 P17787 1/20 0.30
CHRNA4 P43681 1/20 0.30

Click a target to see other patent compounds predicted against it — the reverse direction, in place.

Similar compounds — the chemically nearest patent molecules

Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.

Compoundsimilaritytop predictedshared targets
SCHEMBL9145501 0.98
SCHEMBL9144103 0.98
SCHEMBL6439357 0.85 HTR6 (0.32) HTR6CHRNB2CHRNA4
SCHEMBL9146416 0.84 HDAC3 (0.32)
SCHEMBL9145846 0.84 HDAC3 (0.32)
SCHEMBL9144106 0.83 HTR1A (0.33) HTR6CHRNB2CHRNA4
SCHEMBL8770454 0.75 CHRNB2 (0.32) CHRNB2CHRNA4
SCHEMBL11229784 0.74 HTR6 (0.41) HTR6
SCHEMBL9146479 0.73 CHRNB2 (0.32) CHRNB2CHRNA4
SCHEMBL9140860 0.73 CHRNB2 (0.32) CHRNB2CHRNA4

Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.

Patent provenance — the patents this molecule appears in, and who filed them

Claimed or disclosed in 2 patents. claimed = in the patent's claims; disclosed = body only.

PatentTitleAssigneePublishedPriorityFilingCountryStatus
EP-0569249-B1 Ethylene/alpha-olefin copolymers NIPPON OIL CO LTD (JP) 1997-08-06 EP disclosed
EP-0569249-A2 Ethylene/alpha-olefin copolymers NIPPON OIL COMPANY, LIMITED (JP) 1993-11-10 EP disclosed