Predicted protein targets (top 16)
| gene | UniProt | supporting neighbours | confidence | |
|---|---|---|---|---|
| ▸ | MAPT | P10636 | 5/20 | 0.63 |
| ▸ | RAB9A | P51151 | 2/20 | 0.63 |
| ▸ | TSHR | P16473 | 2/20 | 0.59 |
| ▸ | L3MBTL1 | Q9Y468 | 2/20 | 0.59 |
| ▸ | TDP1 | Q9NUW8 | 1/20 | 0.59 |
| ▸ | MAPK1 | P28482 | 2/20 | 0.51 |
| ▸ | KDM4E | B2RXH2 | 6/20 | 0.50 |
| ▸ | SMN1; SMN2 | Q16637 | 4/20 | 0.50 |
| ▸ | LMNA | P02545 | 3/20 | 0.50 |
| ▸ | ALDH1A1 | P00352 | 2/20 | 0.50 |
| ▸ | HPGD | P15428 | 1/20 | 0.50 |
| ▸ | NPC1 | O15118 | 1/20 | 0.49 |
| ▸ | GAA | P10253 | 1/20 | 0.47 |
| ▸ | POLB | P06746 | 1/20 | 0.46 |
| ▸ | VDR | P11473 | 1/20 | 0.46 |
| ▸ | TP53 | P04637 | 1/20 | 0.45 |
Click a target to see other patent compounds predicted against it — the reverse direction, in place.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| SCHEMBL1122737 | 0.87 | PKM (0.60) | MAPTRAB9ATSHRL3MBTL1MAPK1 | |
| SCHEMBL1122629 | 0.86 | CYSLTR1 (0.57) | MAPTRAB9ATSHRL3MBTL1MAPK1 | |
| SCHEMBL5936640 | 0.86 | PARP10 (0.60) | MAPTRAB9ATSHRL3MBTL1KDM4E | |
| SCHEMBL5284759 | 0.79 | MAPT (1.00) | MAPTRAB9ATSHRL3MBTL1TDP1 | |
| SCHEMBL1951546 | 0.78 | MAPT (1.00) | MAPTRAB9AL3MBTL1TDP1KDM4E | |
| SCHEMBL1122623 | 0.78 | GAA (0.64) | RAB9ATSHRLMNAALDH1A1GAA | |
| SCHEMBL1123321 | 0.76 | KMT2A (0.57) | TSHRL3MBTL1KDM4ESMN1; SMN2ALDH1A1 | |
| SCHEMBL24844734 | 0.74 | MAPT (0.90) | MAPTRAB9ATSHRL3MBTL1TDP1 | |
| SCHEMBL6539224 | 0.74 | MAPT (0.90) | MAPTRAB9ATSHRL3MBTL1TDP1 | |
| SCHEMBL386165 | 0.74 | MAPT (0.89) | MAPTRAB9AL3MBTL1TDP1KDM4E |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 3 patents. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| EP-1644321-B1 | NEW BENZAMIDES AS PPATY MODULATORS | S A L V A T LAB SA (ES) | 2011-02-09 | — | — | EP | disclosed |
| EP-1644321-A2 | NEW BENZAMIDES AS PPATY MODULATORS | LABORATORIOS S.A.L.V.A.T., S.A. (ES) | 2006-04-12 | — | — | EP | disclosed |
| WO-2004110983-A2 | NEW BENZAMIDES AS PPARϒ MODULATORS | LABORATORIOS S.A.L.V.A.T., S.A. (ES) | 2004-12-23 | — | — | WO | disclosed |