Predicted protein targets (top 20)
| gene | UniProt | supporting neighbours | confidence | |
|---|---|---|---|---|
| ▸ | CYSLTR1 | Q9Y271 | 1/20 | 0.57 |
| ▸ | TSHR | P16473 | 2/20 | 0.56 |
| ▸ | LMNA | P02545 | 2/20 | 0.54 |
| ▸ | MAPK1 | P28482 | 2/20 | 0.54 |
| ▸ | TP53 | P04637 | 1/20 | 0.54 |
| ▸ | KDM4E | B2RXH2 | 4/20 | 0.54 |
| ▸ | ALDH1A1 | P00352 | 2/20 | 0.54 |
| ▸ | MAPT | P10636 | 1/20 | 0.49 |
| ▸ | RAB9A | P51151 | 1/20 | 0.49 |
| ▸ | PPARG | P37231 | 3/20 | 0.48 |
| ▸ | VDR | P11473 | 2/20 | 0.48 |
| ▸ | ESR1 | P03372 | 1/20 | 0.48 |
| ▸ | THRA | P10827 | 1/20 | 0.48 |
| ▸ | THRB | P10828 | 1/20 | 0.48 |
| ▸ | RXRA | P19793 | 1/20 | 0.48 |
| ▸ | PPARD | Q03181 | 1/20 | 0.48 |
| ▸ | PPARA | Q07869 | 1/20 | 0.48 |
| ▸ | ESR2 | Q92731 | 1/20 | 0.48 |
| ▸ | SMN1; SMN2 | Q16637 | 2/20 | 0.46 |
| ▸ | CYP1A2 | P05177 | 1/20 | 0.46 |
Click a target to see other patent compounds predicted against it — the reverse direction, in place.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| SCHEMBL1123321 | 0.88 | KMT2A (0.57) | CYSLTR1TSHRKDM4EALDH1A1PPARD | |
| SCHEMBL1123053 | 0.86 | MAPT (0.63) | TSHRLMNAMAPK1TP53KDM4E | |
| SCHEMBL385706 | 0.78 | RAB9A (0.59) | CYSLTR1MAPK1TP53ALDH1A1MAPT | |
| SCHEMBL1122737 | 0.76 | PKM (0.60) | TSHRMAPK1TP53KDM4EALDH1A1 | |
| SCHEMBL5936640 | 0.75 | PARP10 (0.60) | TSHRKDM4EALDH1A1MAPTRAB9A | |
| SCHEMBL6283857 | 0.75 | CYP4F2 (0.58) | CYSLTR1TP53ALDH1A1MAPTRAB9A | |
| SCHEMBL2340354 | 0.75 | KMT2A (0.71) | CYSLTR1TSHRLMNAMAPK1ALDH1A1 | |
| SCHEMBL20740676 | 0.74 | DHFR (0.48) | CYSLTR1TSHRLMNAMAPK1TP53 | |
| SCHEMBL1989028 | 0.74 | KMT2A (0.62) | CYSLTR1LMNAMAPK1ALDH1A1MAPT | |
| SCHEMBL3236755 | 0.74 | RAB9A (0.51) | CYSLTR1TP53KDM4EALDH1A1MAPT |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 3 patents. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| EP-1644321-B1 | NEW BENZAMIDES AS PPATY MODULATORS | S A L V A T LAB SA (ES) | 2011-02-09 | — | — | EP | disclosed |
| EP-1644321-A2 | NEW BENZAMIDES AS PPATY MODULATORS | LABORATORIOS S.A.L.V.A.T., S.A. (ES) | 2006-04-12 | — | — | EP | disclosed |
| WO-2004110983-A2 | NEW BENZAMIDES AS PPARϒ MODULATORS | LABORATORIOS S.A.L.V.A.T., S.A. (ES) | 2004-12-23 | — | — | WO | disclosed |