Predicted protein targets (top 15)
| gene | UniProt | supporting neighbours | confidence | |
|---|---|---|---|---|
| ▸ | KMT2A | Q03164 | 1/20 | 0.57 |
| ▸ | TSHR | P16473 | 1/20 | 0.55 |
| ▸ | GPBAR1 | Q8TDU6 | 1/20 | 0.54 |
| ▸ | CYSLTR1 | Q9Y271 | 1/20 | 0.54 |
| ▸ | KDM4E | B2RXH2 | 2/20 | 0.50 |
| ▸ | ALDH1A1 | P00352 | 1/20 | 0.50 |
| ▸ | NR4A2 | P43354 | 1/20 | 0.50 |
| ▸ | L3MBTL1 | Q9Y468 | 1/20 | 0.48 |
| ▸ | PLA2G4B | P0C869 | 1/20 | 0.47 |
| ▸ | NR1H4 | Q96RI1 | 3/20 | 0.46 |
| ▸ | TBXAS1 | P24557 | 1/20 | 0.46 |
| ▸ | PPARD | Q03181 | 1/20 | 0.46 |
| ▸ | PKM | P14618 | 1/20 | 0.46 |
| ▸ | SMN1; SMN2 | Q16637 | 1/20 | 0.46 |
| ▸ | AKR1C3 | P42330 | 1/20 | 0.46 |
Click a target to see other patent compounds predicted against it — the reverse direction, in place.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| SCHEMBL1122629 | 0.88 | CYSLTR1 (0.57) | TSHRCYSLTR1KDM4EALDH1A1L3MBTL1 | |
| SCHEMBL1122737 | 0.86 | PKM (0.60) | TSHRGPBAR1KDM4EALDH1A1NR4A2 | |
| SCHEMBL6932542 | 0.79 | KMT2A (0.75) | KMT2ANR4A2L3MBTL1PLA2G4BNR1H4 | |
| SCHEMBL10787479 | 0.79 | KMT2A (0.80) | KMT2ANR4A2PLA2G4BNR1H4TBXAS1 | |
| SCHEMBL30167982 | 0.79 | KMT2A (0.80) | KMT2ANR4A2PLA2G4BNR1H4TBXAS1 | |
| SCHEMBL1122793 | 0.78 | L3MBTL1 (0.47) | KMT2ANR4A2L3MBTL1 | |
| SCHEMBL5936640 | 0.77 | PARP10 (0.60) | TSHRKDM4EALDH1A1L3MBTL1PKM | |
| SCHEMBL5936690 | 0.76 | PDPK1 (0.55) | KMT2ATSHRKDM4EALDH1A1TBXAS1 | |
| SCHEMBL1123053 | 0.76 | MAPT (0.63) | TSHRKDM4EALDH1A1L3MBTL1SMN1; SMN2 | |
| SCHEMBL9803295 | 0.76 | KMT2A (0.80) | KMT2ANR4A2PLA2G4BNR1H4TBXAS1 |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 2 patents. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| EP-1644321-B1 | NEW BENZAMIDES AS PPATY MODULATORS | S A L V A T LAB SA (ES) | 2011-02-09 | — | — | EP | disclosed |
| US-20060160894-A1 | Benzamides as ppar modulators | LABORATORIOS S.A.L.V.A.T.,S.A. (ES) | 2006-07-20 | — | — | US | disclosed |
Patent text — is the patent's own abstract consistent with the prediction?
For each of this compound's patents that has machine-readable text (1 of them — usually the abstract, not the full specification), we ask MedCPT which protein the text reads most about, and where the chemistry-predicted target lands among 4885 human targets. A high rank means the patent's own wording is consistent with the prediction — a weak, independent signal, not proof of activity.
| Patent | Title | Text reads most about | Predicted target · text-rank |
|---|---|---|---|
| US-20060160894-A1 | Benzamides as ppar modulators | PPARD, PPARA, PPARG | KMT2A 1515/4885TSHR 240/4885GPBAR1 173/4885 |
“Text reads most about” is the patent abstract's nearest protein in MedCPT space (background-debiased). Only ~1.4% of patents have machine-readable text, so most compounds won't have this panel.